Research

Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA. Read More

Vanderbilt researchers used pharmacological manipulations to increase salt and water transport by kidney cells grown in culture, a step necessary for realizing an implantable artificial kidney device. Read More

Vanderbilt Vaccine Center team isolates monoclonal antibodies against the mosquito-borne Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months. Read More

Vanderbilt researchers discover how anthrax bacterium defends itself against structural damage and resists the toxicity of the antimicrobial drug targocil. Read More

Zhijun Yin, PhD, assistant professor of Biomedical Informatics at Vanderbilt University Medical Center, has received the National Cancer Institute’s Method to Extend Research in Time Award (or MERIT Award) for Early Stage Investigators. Read More

Researchers have developed a method to identify the primary interactions between incoming viral RNA genomes and host proteins. Read More

Computed tomography scans for people at risk for lung cancer lead to earlier diagnoses and improve survival rates, but they can also lead to overtreatment when suspicious nodules turn out to be benign. Read More

John York and colleagues have demonstrated that the protein Vip1 is a rare type of bifunctional enzyme: it can both synthesize and destroy key cellular signaling molecules. Read More

New findings suggest that dietary calcium and magnesium affect the risk of esophageal cancer; if confirmed in interventional studies, they could inform dietary modifications to reduce the burden of this cancer. Read More

Electronic health records and biobanks can be effectively combined to detect and study Mendelian diseases such as cystic fibrosis. Read More

Monoclonal antibodies against Marburg virus — a more lethal cousin of the RNA virus that causes COVID-19 — may aid in the development of antibody "cocktails" to counter viral infection. Read More

Vanderbilt University has established a new COVID-19 Research and Innovation Fund. The fund enables donations to support research and innovation projects to fight COVID-19. Read More

Mechanical engineering professors Joshua Caldwell and Kelsey Hatzell are inaugural recipients of Flowers Family faculty awards. Caldwell is the Flowers Family Chancellor Faculty Fellow in Engineering. Hatzell is the Flowers Family Dean's Faculty Fellow in Engineering. Read More

An international research team that includes Vanderbilt engineers is the first to successfully separate two ions with very, very small size differences, a major advancement in separation science with widespread potential application. Read More

A disease-associated mutation in a transporter protein impairs gut barrier function, leading to gastrointestinal disease and chronic infections. Read More

Parents of children with autism spectrum disorders benefited from the addition of mindfulness-based stress reduction to parent-implemented behavioral interventions. Read More

Dylan Burnette and colleagues have discovered that two forms of the molecular motor protein myosin have distinct roles in regulating cell shape during cell division. Read More

New findings suggest that treatments that decrease oxidative damage might help with postoperative delirium that occurs in up to 30% of cardiac surgery patients. Read More

The paper, sharing findings from a study of pyrite nanoparticles led by undergraduate mechanical engineering student Masahiro Kato and Ph.D. students Nicole Moering and Madeleine Fort, appeared this week in Materials Today Advances. Read More