Research
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COVID-19 antibody ‘cocktail’ discovered at VUMC protects chronically ill: study
A monoclonal antibody cocktail against the COVID-19 virus discovered at VUMC is the first non-vaccine modified to demonstrate the prevention of COVID-19 in a clinical trial of more than 5,000 participants. The antibody treatment could afford up to 12 months of protection from COVID-19, and preliminary laboratory findings also suggest that it can neutralize the delta variant. Read MoreAug 20, 2021
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Potential protection from atherosclerosis
Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins. Read MoreAug 19, 2021
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New departments answer growing demand in computer science, computational science, electrical engineering
Music Row becomes Technology Row The School of Engineering has created two new departments from the Department of Electrical Engineering and Computer Science to encourage innovation, accommodate enrollment growth, and focus on areas of strategic excellence. The existing degree programs in computer science will be housed in the new Department of Computer Science chaired by... Read MoreAug 18, 2021
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Vitamin D impact on disease biomarkers
In a randomized controlled trial, vitamin D supplementation did not improve biomarkers for cardiovascular and metabolic disease. Read MoreAug 10, 2021
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Sudden death from deep in the brain?
Vanderbilt neurologists found altered excitability in deep brain structures that they note may drive respiratory dysfunction and sudden death in a rare form of epilepsy. Read MoreAug 9, 2021
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Motor protein linked to intestinal cell differentiation
The motor protein MYO5B, a cause of the congenital intestinal disorder microvillus inclusion disease, does more than move cellular cargo, Vanderbilt researchers have discovered. Read MoreAug 5, 2021
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Gene expression in diabetic nephropathy
Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease. Read MoreAug 5, 2021
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Discovery points to new avenues to kill aggressive cancer cells
Chemoresistant SW480 colon cancer cells stained for lipid rafts (green), death receptor 4 (red) and cell nuclei (blue). Image taken by Joshua Greenlee using a Zeiss LSM 880 from the Vanderbilt Cell Imaging Shared Resource Center. By Marissa Shapiro THE IDEA Vanderbilt faculty and researchers are looking for the “Achilles’ heel” of the cancer cells... Read MoreAug 3, 2021
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Discovery points to new avenues to kill aggressive cancer cells
Chemoresistant SW480 colon cancer cells stained for lipid rafts (green), death receptor 4 (red) and cell nuclei (blue). Image taken by Joshua Greenlee using a Zeiss LSM 880 from the Vanderbilt Cell Imaging Shared Resource Center. By Marissa Shapiro THE IDEA Vanderbilt faculty and researchers are looking for the “Achilles’ heel” of the cancer cells... Read MoreAug 3, 2021
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Prediction models for breast cancer
Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction. Read MoreJul 27, 2021
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NSF virtual expo this week highlights 3 major projects led by VUSE faculty
Three ambitious, multidisciplinary projects led by Vanderbilt School of Engineering faculty will be featured Wednesday and Thursday, July 28 and 29, during the NSF Convergence Accelerator Expo 2021. The two-day virtual event will present 15-minute demonstrations of novel solutions that address big-scale societal challenges. The NSF-funded projects integrate disciplines and include industry partners from their... Read MoreJul 26, 2021
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NSF virtual expo this week highlights three major projects led by VUSE faculty
Three ambitious, multidisciplinary projects led by Vanderbilt School of Engineering faculty will be featured Wednesday, July 28, and Thursday, July 29, during the National Science Foundation Convergence Accelerator Expo 2021. Read MoreJul 26, 2021
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Mood and cognition after chemotherapy
Validation of cognitive complaints appears to improve mood in patients with persistent chemotherapy-cognitive impairment, Vanderbilt researchers report. Read MoreJul 26, 2021
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Researchers discover that protein switches functions to regulate DNA replication
Vanderbilt biochemists have discovered that the protein RADX has different biological effects at sites of DNA synthesis, depending on the cellular conditions — even though it works the same way in both stressed and unstressed cells. Read MoreJul 22, 2021
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For more precise drug treatments, ‘squeeze’ the genome: study finds
Large-scale studies will be required to identify the complexity of genetic variations that affect how patients respond to a given drug and whether they will have side effects, according to researchers at Vanderbilt University Medical Center. Read MoreJul 22, 2021
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Influenza network sizes up COVID
Hospital data from a CDC network that monitors influenza revealed that adults hospitalized for COVID-19 in the early months of the pandemic were 20x more likely to die compared to hospitalized influenza patients. Read MoreJul 22, 2021
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Team wins competitive DOE award to advance isotope production critical for U.S. science, medicine and industry
A U.S. Department of Energy $4 million initiative to advance research in isotope production includes a Vanderbilt engineering professor’s work on separation technologies and to scale up processes. The funding is part of a key federal program that produces critical isotopes otherwise unavailable or in short supply for U.S. science, medicine and industry. Piran Kidambi,... Read MoreJul 22, 2021
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Team wins competitive DOE award to advance isotope production critical for U.S. science, medicine and industry
A U.S. Department of Energy $4 million initiative to advance research in isotope production includes a Vanderbilt engineering professor’s work on separation technologies and to scale up processes. The funding is part of a key federal program that produces critical isotopes otherwise unavailable or in short supply for U.S. science, medicine and industry. Piran Kidambi,... Read MoreJul 22, 2021
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$1.5M DOE grant targets engineering of cyanobacteria as biofuel production platform
A new, $1.5 million Department of Energy grant brings together experts from three institutions to parse the metabolism of a blue-green algae that holds great promise for biofuel production. The team, led by Professor of Chemical and Biomolecular Engineering Jamey Young, will take a systems biology approach to identify how cyanobacteria, also known as blue-green... Read MoreJul 20, 2021
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$1.5M DOE grant targets engineering of cyanobacteria as biofuel production platform
A new, $1.5 million Department of Energy grant brings together experts from three institutions to parse the metabolism of a blue-green algae that holds great promise for biofuel production. The team, led by Professor of Chemical and Biomolecular Engineering Jamey Young, will take a systems biology approach to identify how cyanobacteria, also known as blue-green... Read MoreJul 20, 2021