PNAS
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Mouse model for autism yields clues to a 50-year-old mystery
A genetic variation that causes early disruptions in serotonin signaling in the brain may contribute to autism spectrum disorder and other enduring effects on behavior. Read MoreMar 20, 2012
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‘Detangler’ binds, bends and cuts DNA
New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents. Read MoreMar 2, 2012
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Alcohol’s molecular mediators
Therapeutic agents focusing on the brain region involved in stress-induced relapse may be effective in preventing relapse in patients with alcohol use disorders. Read MoreJan 23, 2012
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Gene ‘signature’ may predict cancer outcomes
A gene signature may be useful in predicting outcomes for patients with rhabdomysarcoma, a form of cancer most commonly diagnosed in children. Read MoreMar 25, 2011
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Breast cancer vulnerable to multi-hit therapy
Combining targeted therapies may increase their effectiveness in treating a common and aggressive form of breast cancer. Read MoreMar 21, 2011
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Protein combos keep cells straight
Researchers define the protein interactions that establish our organs' lining. Read MoreMar 18, 2011