Pharmacology
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Amanda Linkous advances lung cancer research with Merck Research Laboratories Scientific Engagement and Emerging Discovery Science program
Amanda Linkous, research associate professor of pharmacology, has been awarded a research grant from the Merck Research Laboratories Scientific Engagement and Emerging Discovery Science (SEEDS) program to identify therapeutic intervention points to prevent the colonization and proliferation of small cell lung cancer and non-small cell lung cancer in the lung and brain. Read MoreSep 24, 2024
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Promising drug-like compounds found to have strong action against blood cancers
Research from the lab of Bill Tansey and other collaborators tested protein inhibitors called WINi against a panel of cancer cells and found that they have strong action against blood cancers and synergize with an FDA-approved cancer drug. Read MoreSep 5, 2024
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‘Smarter Every Day’ explores how bacteria move to survive—and make us sick
In a recent episode of Smarter Every Day, YouTube sensation and host Destin Sandlin talks with Vanderbilt Professor Tina Iverson and Senior Research Associate Prashant Singh about bacterial “motors” and how they work in the microorganisms that make us sick. The video racked up more than 1.4 million views in its first day. Read MoreJul 30, 2024
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Prestigious $1.3M Keck grant boosts research on alcohol detection, aiding alcohol use disorder treatment
Vanderbilt assistant professor of pharmacology Cody Siciliano has been awarded a $1.3 million grant from the W.M. Keck Foundation to study oral chemesthesis, the burning sensation you feel in your mouth when you sip alcohol. Understanding this sensation better could lead to new treatments for alcohol use disorders, but research in this area is scarce. Read MoreJul 24, 2024
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New drug candidates targeting blood clots developed through computer-aided drug design
Using computer-aided drug design, Heidi Hamm, Craig Lindsley, and Jens Meiler and their labs generated a novel series of biologically active compounds that can serve as a basis for anti–blood clot preventative drugs. Read MoreJun 11, 2024
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Basic science research featured at 2024 Vanderbilt Alzheimer’s Disease Research Day
The Vanderbilt Memory and Alzheimer's Center hosted its fifth Annual Vanderbilt Alzheimer’s Disease Research Day on April 10 with the theme of “big data.” Aside from presentations from faculty from across campus and the School of Medicine Basic Sciences, the day featured data blitzes, a keynote presentation, and a poster reception with more than 45 posters. Read MoreApr 24, 2024
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Nguyen marries basic and translational approaches to ID new brain region responsible for epileptic seizures
Incoming assistant professor of pharmacology Quynh Anh Nguyen spearheaded research that points to a previously unidentified region of the hippocampus as responsible for epileptic seizures. The work could lead to new avenues of treatment to help epilepsy patients control their seizures. Read MoreApr 23, 2024
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Sean Davies awarded Scaling Success grant to develop small molecules with promise of protecting against cardiometabolic disease
Sean Davies, associate professor of pharmacology and associate director of graduate studies for the department, has been awarded a Scaling Success grant from Research Development and Support in the Office of the Vice Provost for Research and Innovation. Read MoreMar 28, 2024
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Vanderbilt chemist Ben Brown awarded $2.375M to develop nonaddictive painkillers with AI
Avenir Award funding from the National Institute on Drug Abuse recognizes research that represents “the future of addiction science.” Brown’s research is creating an AI-experiment feedback loop that will help optimize painkilling drugs to be less addictive. Read MoreJan 18, 2024
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Watch now: Lab-to-Table Conversation: Beyond Addiction: Therapeutic Developments and Societal Impact
Join the next Lab-to-Table conversation, “Beyond Addiction: Therapeutic Developments and Societal Impact” on Jan. 24 at 11:30 a.m. CT. Read MoreJan 11, 2024
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Quanta Magazine: She studies how addiction hijacks learning in the brain
Erin Calipari works to understand how drugs like opioids and cocaine alter learning circuits and neurochemistry in one of the country's epicenters of substance use disorder and addiction. Read MoreDec 14, 2023
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Vanderbilt Center for Addiction Research joins Discovery Vanderbilt; Calipari appointed director
The Vanderbilt Center for Addiction Research, led by Erin Calipari, advances research to understand how addiction and substance use disorder develops in the brain. VCAR’s goals are to develop new pharmaceutical strategies and to destigmatize addiction as a personal failing. Read MoreDec 14, 2023
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Potential schizophrenia treatment, discovered at Vanderbilt and being developed by Neumora Therapeutics, entering Phase 1 clinical trial
In just over two years, a Vanderbilt-Neumora collaboration has led to the Phase 1 clinical trial of a treatment for schizophrenia spectrum disorders, which affect 3.7 million adults in the United States. This is the third chemical compound discovered at the Warren Center for Neuroscience Drug Discovery to reach Phase 1 clinical trials. Read MoreDec 4, 2023
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Vanderbilt scientists make headway in drug development to cure pulmonary arterial hypertension
Biomedical engineer David Merryman and Warren Center for Neuroscience Drug Discovery director Craig Lindsley have developed a new drug that treats PAH, a type of high blood pressure that affects arteries in the lungs and in the heart, without serious neurological side effects. Read MoreSep 13, 2023
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Lab-to-Table Conversation: ‘Coffee: Where Science Meets Sips’ on Sept. 27
Join “Coffee: Where Science Meets Sips” in the next Lab-to-Table Conversation on Sept. 27. Read MoreSep 13, 2023
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CTTC Announces the Awardees of the 2023 Master Innovator Recognition Program
Vanderbilt's Center for Technology Transfer and Commercialization named Richard Caprioli, C. David Weaver, Susan Eagle, and Franz Baudenbacher 2023 Master Innovators. The yearly recognition program acknowledges Vanderbilt’s top innovators and entrepreneurs for their contributions to the creation, development, and commercialization of intellectual property. Read MoreSep 5, 2023
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Vanderbilt researcher wins grant to study risk factors for Alzheimer’s disease, dementia in older LGBTQ+ adults; experts present at Alzheimer’s conference
Experts in research on Alzheimer’s disease and related dementias share their latest findings at the 2023 Alzheimer’s Association International Conference. Nik Lampe, postdoctoral researcher, was awarded a grant to examine the social and medical factors influencing ADRD using data from VUSNAPS. Read MoreAug 31, 2023
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Basic Sciences names Hodges, Siciliano as Dean’s Faculty Fellows
Emily Hodges, assistant professor of biochemistry, and Cody Siciliano, assistant professor of pharmacology, have been named Dean’s Faculty Fellows of the School of Medicine Basic Sciences. Read MoreAug 21, 2023
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Vanderbilt mourns loss of renowned clinical pharmacologist Jackson Roberts II, MD
Jackson Roberts II, MD, an internationally known clinical pharmacologist in the Vanderbilt University School of Medicine who helped define the role of lipid peroxidation and oxidative stress in human disease, died May 31 in Nashville. He was 79. Read MoreJun 5, 2023
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Lab-to-Table Conversation: ‘Social Media and Addiction’ May 9
How is social media creating conversations about addiction and recovery? How is it building broader community? And how is it a complex space to engage with as a person in recovery? The discussion, led by Erin Calipari, will feature psychiatry experts on May 9. Read MoreApr 27, 2023