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Parkinson’s disease Archives

DBS treatment may slow tremor progression in early-stage Parkinson’s patients

Jun. 29, 2018—Analysis of data from a clinical trial conducted at Vanderbilt suggests that deep brain stimulation (DBS) administered to patients with very early-stage Parkinson’s disease slowed the progression of rest tremor. The study, published June 29 in Neurology, is significant because it is the first evidence of a treatment that may possibly delay the progression of...

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Investigators eye new target for treating movement disorders

Jan. 18, 2018—Blocking a nerve-cell receptor in part of the brain that coordinates movement could improve the treatment of Parkinson’s disease, dyskinesia and other movement disorders, researchers at Vanderbilt University have reported.

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Impulsivity in Parkinson’s Disease

Oct. 27, 2017—A noninvasive MRI technique may help predict a troubling side effect of common medications for Parkinson’s Disease and improve clinical treatment plans.

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Trial to test whether DBS slows Parkinson’s progression

Sep. 1, 2016—A consortium led by Vanderbilt University Medical Center (VUMC) researchers has received funding as it makes plans for a multicenter trial that could determine whether deep brain stimulation (DBS) slows the progression of Parkinson’s disease in early-stage patients.

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Deep brain stimulation program marks milestones

Mar. 24, 2016—Vanderbilt Clinical Neurosciences is marking two milestones — the 20th anniversary of its deep brain stimulation (DBS) program and its 1,000th DBS procedure.

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Neimat: Emotional disturbance is an overlooked symptom of Parkinson’s

Oct. 22, 2015—Despite benefiting from dramatic improvements in movement after deep brain stimulation surgery, patients with Parkinson’s disease can be inadequately served when physicians and researchers focus only on its motor manifestations, says a Vanderbilt neurosurgeon.

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Study sheds light on a ‘guardian’ protein of brain function

Feb. 19, 2015—Mitochondria not only are the cell’s main power producers, they are also the chief cooks and bottle washers.

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Copper toxicity and Parkinson’s

Feb. 5, 2015—A genetic predisposition to Parkinson’s disease makes neurons more vulnerable to the toxicity of heavy metals such as copper.

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New tools to probe manganese biology

Nov. 26, 2014—Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.

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Team takes 4-D look at brain receptor’s role

Aug. 14, 2014—Reporting last week in the journal Cell, researchers from Oregon Health and Science University, Harvard Medical School and Vanderbilt University describe the first “four-dimensional” picture of a brain receptor that plays a key role in learning and memory.

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DBS for Parkinson’s trial moves to next level

Apr. 3, 2014—A long-term Vanderbilt University Medical Center study of deep brain stimulation (DBS) in early-stage Parkinson’s disease has received approval from the Food and Drug Administration (FDA) to continue in a pivotal, phase III, large-scale safety and efficacy trial.

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‘Missing link’ may spur new brain disorder drugs

Mar. 13, 2014—Researchers at the Scripps Research Institute in San Diego and Vanderbilt University have discovered a “missing link” in the structure of a transmembrane receptor that could lead to new treatments for autism, schizophrenia, Parkinson’s disease and Alzheimer’s disease.

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