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obesity Archives

Enzyme protects against obesity-related heart disease

Jun. 7, 2018—Vanderbilt scientists have discovered that a certain enzyme plays a crucial role in preventing obesity-related cardiac dysfunction.

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Characterizing ‘keyhole’ is first step to fighting obesity at the cellular level

Apr. 18, 2018—A Vanderbilt team and their international colleagues characterized for the first time a complex, little-understood cellular receptor type that, when activated, shuts off hunger.

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Voluntary exercise and energy balance

Mar. 23, 2018—Non-exercise physical activity has a measurable energy expenditure, which goes down when animals engage in voluntary exercise, Vanderbilt researchers have discovered.

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Study explores best pre-transplant weight loss options

Feb. 8, 2018—Vanderbilt researchers are comparing two types of weight-loss options to determine which is the most effective in helping obese patients reach a more ideal weight before undergoing kidney transplant surgery.

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Rising obesity rates in South leading to rapid increase in diabetes

Jan. 18, 2018—Rising obesity rates in several Southern states are leading to a rapid increase in new cases of diabetes among both black and white adults. A new study helmed by investigators at the University of Texas Health Science Center and Vanderbilt University Medical Center (VUMC) found the risk of diabetes is double for black patients.

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Obesity interventions: ideal dose?

Dec. 21, 2017—The optimal “dose” for behavioral interventions to treat childhood obesity are not clear, Vanderbilt researchers concluded after analyzing 133 clinical trial that occurred over the course of 17 years.

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Inhibiting obesity

Sep. 15, 2017—An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain.

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VUMC joins cutting-edge obesity research network

Mar. 16, 2017—Vanderbilt University Medical Center (VUMC) is one of four centers receiving a $15 million, four-year research award from the American Heart Association (AHA) to provide cutting-edge research on obesity as part of its sixth Strategically Focused Research Network (SFRN).

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Saliva test for obesity risk

Jan. 24, 2017—“Epigenetic signatures” in DNA may present an opportunity for prevention of or early intervention in childhood obesity.

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BMI genotype and breast cancer risk

Sep. 29, 2016—For breast cancer prevention, a new study provides evidence for lifestyle modification to reduce weight gain in adults.

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Nervous system’s role in hypertension

Aug. 29, 2016—Increased activity of the “fight or flight” nervous system contributes to obesity-associated hypertension and may be a good therapeutic target for the disease.

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Possible overeating antidote

Aug. 1, 2016—The 2C-subtype of the serotonin receptor (5HT2C), which binds the neurotransmitter serotonin, plays an important role in regulating food intake and metabolism.

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