NINDS

Vanderbilt investigators have discovered that functional MRI detects neural activity in both gray and white matter in the brain, suggesting new ways to investigate diseases such as Alzheimer’s and multiple sclerosis. Read More

A noninvasive MRI technique may help predict a troubling side effect of common medications for Parkinson’s Disease and improve clinical treatment plans. Read More

Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation. Read More

Assessing brain functional and structural connectivity in patients with temporal lobe epilepsy may be a useful way to identify the best candidates for surgical treatment. Read More

Understanding how mutations affect the structure and function of inhibitory neurotransmitter receptors will shed light on the mechanisms underlying some types of epilepsy. Read More

Genetic variation in GABA-A receptors confers risk for inherited forms of epilepsy. Read More

Collybolide – a natural product isolated from a mushroom – is a promising candidate for the development of non-addictive pain medicines. Read More

A new animal model can be used to “dissect” the inflammatory response to infection. Read More

Vanderbilt investigators have defined a gene expression program that controls the timing of synaptic remodeling – a process that is critical to brain development, learning and memory. Read More

Vanderbilt researchers are exploring how neuroblastoma tumors begin and progress, knowledge that could provide new treatments for this pediatric cancer. Read More

Vanderbilt investigators report the first use of a specialized type of MRI to study the hippocampus in patients with schizophrenia. Read More

A novel mechanism could point to new therapies for a group of inherited diseases that share pathological features. Read More

A genetic predisposition to Parkinson’s disease makes neurons more vulnerable to the toxicity of heavy metals such as copper. Read More

Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist. Read More

Patients with orthostatic intolerance – problems when standing – have cognitive changes, even when seated, compared to healthy individuals. Read More

An overactive stress response contributes to the development of insulin resistance in obese individuals, and blocking it may be therapeutically beneficial. Read More

A particular neuronal cell population is involved in the pathogenesis of a rare neurological disorder, Vanderbilt researchers have discovered. Read More

Drugs developed at Vanderbilt could provide a new way to treat schizophrenia in a personalized way. Read More

A protein in the myelin coating on nerves helps form a “seal” that enables effective nerve conduction; loss of the protein causes inherited neuropathies. Read More

Vanderbilt researchers have discovered that variation in the gene encoding the potassium channel GIRK1 plays a role in modulating human pain perception. Read More