NIH

Signaling pathway discoveries suggest ways to induce stem cells to become cardiac muscle cells, which could be useful for regenerating damaged heart muscle. Read More

Brain deficits are not present in the early stages of schizophrenia, suggesting it may be possible to delay or prevent the development of brain abnormalities. Read More

New details about the life cycle of respiratory syncytial virus (RSV) could aid the development of therapies to combat this leading cause of serious illness in infants and the elderly. Read More

In this Tennessean opinion piece, Vice Chancellor for Health Affairs Jeff Balser discusses the impact scientific research has in Tennessee and the critical importance of continued federal investment in this research. Read More

A new study found that lower-calorie tube feedings do not reduce a patient’s ventilator use. Read More

A new analytical tool points to genes that act together to increase disease risk. Read More

Treatment with a drug used to prevent organ rejection partially reverses the course of tuberous sclerosis, research in mice suggests. Read More

Drugs that target “epigenetic” changes may help treat or slow the progression of lung cancer. Read More

A protein involved in repairing DNA damage associated with gastric reflux may play a tumor suppressor role in the esophagus and could represent a target for therapies to combat esophageal cancer. Read More

Therapeutic agents focusing on the brain region involved in stress-induced relapse may be effective in preventing relapse in patients with alcohol use disorders. Read More

The discovery of a previously unrecognized and pivotal role of enzyme ASL in nitric oxide production could potentially lead to new therapies for babies with pulmonary hypertension. Read More

The Vanderbilt Digestive Disease Research Center celebrates its 10th anniversary this year with a second five-year renewal of its federal research grant. Read More

A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications. Read More

In addition to body mass index, genetic markers of obesity may provide value in predicting endometrial cancer risk. Read More

Images of individuals with Alagille syndrome (National Institutes of Health) Mutations in the Jagged1 gene cause Alagille syndrome, an inherited disorder that affects the liver, heart, kidneys and facial structure. Patients with Alagille syndrome often have a prominent forehead, a flattened midface and a prominent chin; some have a cleft… Read More

The progression of new drug candidates for schizophrenia with partner Janssen Pharmaceutica is the latest evidence that a new collaborative model for drug discovery pioneered at Vanderbilt may help identify and develop innovative candidate drugs for treatment of major brain disorders. Read More

Protein helps ensure proper division of chromosomes during cell division. Read More

Host cell protein may be a target for strategies to limit spread of virus-induced squamous cell cancers. Read More

Molecular players involved in colon cancer progression could provide new biomarkers to indicate invasiveness and prognosis. Read More

A Vanderbilt study shows that a class of drugs used to treat autoimmune diseases does not increase the chance of hospitalization for serious infection. Read More