NIH
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Host proteins can control HIV infection
The protein APOBEC3G contributes to spontaneous control of HIV-1 in vivo and may provide therapeutic benefits. Read MoreOct 5, 2012
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Proteins help flip tumor’s invasive switch
Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together. Read MoreOct 4, 2012
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An orphan enzyme’s purpose
“Orphan” enzyme may play role in cancer growth, new research suggests. Read MoreOct 4, 2012
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AAMC meet highlights need for research funds
During a meeting in Nashville last week, the director of the National Institutes of Health (NIH) called on academic medical centers to make the case for continued, strong federal investment in biomedical research. Read MoreSep 27, 2012
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Target acquired for aggressive tumor
New therapeutic target for angiosarcoma – an aggressive, highly fatal tumor of the blood vessels – identified. Read MoreSep 27, 2012
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Cell entry ports for cold virus
The respiratory virus HMPV uses its fusion (F) protein – which interacts with cellular receptors called integrins – to bind to and enter target cells. Read MoreSep 25, 2012
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HER2 may impact lung cancer therapy
A protein associated with aggressive breast cancers may also influence resistance of lung cancer to targeted therapies. Read MoreSep 21, 2012
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How ‘Jedi’ disposes of dead neurons
The protein Syk is essential for clearing away neuron “corpses” in the developing peripheral nervous system. Read MoreSep 19, 2012
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Caving for Cures project gains museum limelight
If you drop by the American Museum of Natural History the next time you visit New York, there is a good chance that you will see an exhibit highlighting Vanderbilt chemist Brian Bachmann’s "caving for drugs" research. Read MoreSep 17, 2012
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Cells with LIP eat their neighbors
A transcription factor called LIP is capable of causing one cell to consume another. Read MoreSep 13, 2012
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Enzyme counters stomach acid attack
Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease. Read MoreSep 11, 2012
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Parkinson’s therapy may impact language
Deep brain stimulation used to treat Parkinson’s disease may impair some aspects of language processing, a recent study suggests. Read MoreSep 7, 2012
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Neuronal subtypes in genetic disorder
Inhibitory neurons that connect and regulate signaling in the brain (interneurons) may contribute to epilepsy and autism in patients with tuberous sclerosis complex. Read MoreSep 6, 2012
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Clues to retinal cell degeneration
A reversible chemical modification of rhodopsin, a receptor for light, plays a role in the degeneration of retinal cells. Read MoreAug 28, 2012
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Tool helps plumb electronic records
A tool developed for one institution’s electronic health records can work at other institutions, potentially facilitating the use of these records in research studies. Read MoreAug 24, 2012
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African ancestry, stomach bug link
Socioeconomic factors, African ancestry linked to risk for cancer-causing infection. Read MoreAug 16, 2012
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Key to a woman’s heart (condition)?
Females may be at higher risk of potentially fatal heart condition due to gender differences in a protein involved in the heart’s electrical activity. Read MoreAug 10, 2012
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New therapeutic target for cold, flu viruses identified
Viruses that cause acute respiratory infections — such as human metapneumovirus (HMPV) and flu — impair a set of immune system cells that should clear the virus from the lungs. Now, Vanderbilt University investigators have discovered the signaling pathway that disables these immune cells. Read MoreAug 9, 2012
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Study tracks how gene may promote lung cancer tumors
Vanderbilt-Ingram Cancer Center researchers have identified how one of the genes most commonly mutated in lung cancer may promote such tumors. Read MoreAug 9, 2012
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Network approach yields glioblastoma clues
MicroRNA “regulatory networks” generated at Vanderbilt aid search for biomarkers and new drugs to treat glioblastoma, the most common and lethal primary brain tumor. Read MoreAug 9, 2012