NIH

The protein MTBP is overexpressed in an aggressive type of breast cancer, and it regulates another protein implicated in many cancer types, suggesting that it may be a good target for new therapeutics. Read More

Understanding how the immune system responds to the respiratory virus HMPV is crucial for developing vaccines and anti-viral treatments. Read More

Augmenting the signals of natural “endocannabinoids” in the brain may be a promising approach for treating mood and anxiety disorders. Read More

A newly identified receptor allows mammalian reovirus to infect neurons, shedding light on factors important for viral encephalitis. Read More

Understanding how to control the generation of regulatory T cells could have important implications for treating autoimmunity and cancer. Read More

A novel molecular “conversation” regulates kidney fibrosis – the final result of end-stage chronic kidney disease – suggesting new treatment options for this currently irreversible process. Read More

Armed with a $7.2 million grant from the National Institutes of Health, Vanderbilt University Medical Center is one of six medical centers around the country selected to participate in a network to develop effective approaches for diagnosing hard-to-solve medical cases. Read More

Armed with a $7.2 million grant from the National Institutes of Health (NIH) Vanderbilt University Medical Center is one of six medical centers around the country selected to participate in a network to develop effective approaches for diagnosing hard-to-solve medical cases (undiagnosed diseases). Read More

Vanderbilt researcher Bernard Rousseau, Ph.D., is being appointed to the Motor Function, Speech and Rehabilitation Study Section at the Center for Scientific Review, National Institutes of Health, for the term beginning July 1 and ending June 30, 2020. Read More

New views of how transporters move molecules across cell membranes are key to understanding how these proteins impact tumor cell drug resistance and inherited diseases such as cystic fibrosis. Read More

Dan Roden, M.D., assistant vice chancellor for Personalized Medicine, has been appointed to the National Advisory Council for Human Genome Research of the National Institutes of Health (NIH). Read More

Virus-like particles containing a protein from human metapneumovirus are a promising vaccine candidate for this respiratory virus. Read More

Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer. Read More

The contractile machinery inside tumor cells increases invasive properties, suggesting it might be a good target to inhibit cancer cell spread. Read More

The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion. Read More

A particular anti-arrhythmia drug provides a targeted treatment for certain forms of atrial fibrillation. Read More

Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage. Read More

A novel PET imaging probe detects tumor cell death in vivo and could be useful for personalizing cancer medicine. Read More

A genetic variant is associated with toxicity of the chemotherapy drug melphalan, and could guide individualized dosing for the medication. Read More

Understanding how chikungunya virus binds to and enters cells offers a new target for antiviral medications. Read More