NIH

Actin and microtubule cytoskeletons are coordinated during cytokinesis – the process that separates one cell into two and is linked to events underlying cancer. Read More

Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy. Read More

Researchers at Vanderbilt University Medical Center have relieved symptoms in a mouse model of Rett syndrome with a drug-like compound that works like the dimmer switch in an electrical circuit. Read More

Federal officials with the White House and National Institutes of Health (NIH) announced today that Vanderbilt University Medical Center (VUMC) will lead the Direct Volunteers Pilot Studies under the first grant to be awarded in the federal Precision Medicine Initiative Cohort Program. Read More

Vanderbilt researchers have defined a mechanism that limits liver cell proliferation after injury in order to preserve critical metabolic functions. Read More

New findings offer a potential strategy for preventing heritable pulmonary arterial hypertension. Read More

An inability to recognize faces may be an important mechanism underlying social inhibition and may contribute to, or maintain, social anxiety. Read More

Combining therapies for melanoma that induce cell senescence and that activate the immune response may improve outcomes for patients. Read More

The National Institutes of Health (NIH) has awarded Vanderbilt’s Department of Pediatrics a K12 training grant to support early career faculty to become physician-scientists, the first time the department has received such an award. Read More

The first study that directly compares Neanderthal DNA in the genomes of a significant population of adults of European ancestry with their clinical records confirms that this archaic genetic legacy has a subtle but significant impact on modern human biology. Read More

One small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis, Vanderbilt researchers have discovered. Read More

Vanderbilt investigators have discovered a way to overcome the resistance of some lung cancers to certain targeted therapies, which could lead to more effective treatments for lung cancer patients. Read More

Vanderbilt researchers have developed a high-throughput assay that will aid in identifying new compounds to treat preterm labor or postpartum bleeding. Read More

Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease. Read More

Vanderbilt engineers have modified a cotton candy machine to create complex microfluidic networks that mimic the capillary system in living tissue and have demonstrated that these networks can keep cells alive and functioning in an artificial three-dimensional matrix. Read More

Vanderbilt investigators are exploring the shape changes in a multidrug transporter to understand the mechanisms of antibacterial resistance. Read More

A family of proteins with critical roles in cell division, synaptic transmission and cell migration don’t all function the way scientists thought they did, according to two new studies led by Vanderbilt researchers. Read More

A microRNA — a small piece of RNA involved in regulating gene expression — functions as an oncogene to drive the development of lung cancer, Vanderbilt University investigators have discovered. Read More

The elasticity of a scaffold used for healing skin wounds is a key factor in promoting regeneration versus scarring. Read More

Vanderbilt investigators report an improved model for estimating brain health, using MRI. Read More