NICHD

A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage. Read More

The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition. Read More

A newly identified genetic risk factor for heart block after surgery may help guide the course of postoperative care. Read More

The protein beta-catenin may be a good target for therapies to treat lung disease that is a common complication of preterm birth. Read More

“Epigenetic signatures” in DNA may present an opportunity for prevention of or early intervention in childhood obesity. Read More

A new method will make it possible to study solid tumors and healthy tissues using mass cytometry. Read More

Children with Prader-Willi Syndrome who received growth hormone treatment had cognitive advantages compared to untreated patients. Read More

Defining the genes required for the function of insulin-producing beta cells is crucial for ongoing efforts to develop a cell-based therapy for diabetes. Read More

Vanderbilt researchers have developed a high-throughput assay that will aid in identifying new compounds to treat preterm labor or postpartum bleeding. Read More

The enzyme alkaline phosphatase may provide a new therapeutic option for women at high risk of pregnancy complications due to bacterial toxin exposure. Read More

Antibiotic-resistant bacteria can share resources to cause chronic infections, Vanderbilt investigators have discovered. The findings shed light on a long-standing question in infectious diseases and may inform new treatment strategies. Read More

Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis. Read More

The antioxidant vitamin E prevented the buildup of toxic products in a model of a rare genetic disorder, suggesting new strategies for therapeutic development. Read More

Alkaline phosphatase enzymes appear to play roles in promoting pregnancy and in protecting the uterus from bacterial infection. Read More

A biomarker for oxidative stress is elevated in patients with both autism spectrum disorder and gastrointestinal dysfunction, suggesting opportunities for individualized approaches to clinical care. Read More

Antacids that block a certain enzyme pose a risk for a common cardiac problem in premature infants. Read More

An immune system factor associated with severe asthma may actually reduce asthma attacks induced by viral infections. Read More

The gene Has2 participates in signaling that is important in developing fingers and toes, and may have relevance for cancer development. Read More

Individuals with overexpression of the gene MECP2 have core features of autism spectrum disorder. Read More

The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments. Read More