NICHD
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Obesity interventions: ideal dose?
The optimal “dose” for behavioral interventions to treat childhood obesity are not clear, Vanderbilt researchers concluded after analyzing 133 clinical trial that occurred over the course of 17 years. Read MoreDec 21, 2017
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Forming memories through CaMKII
Vanderbilt researchers have identified an interaction between two proteins that play a role in learning and memory. Read MoreDec 19, 2017
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NSAIDs, genetics and miscarriage
A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage. Read MoreSep 20, 2017
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NOTCH1 role in heart development
The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition. Read MoreJul 3, 2017
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Mutation raises heart block risk
A newly identified genetic risk factor for heart block after surgery may help guide the course of postoperative care. Read MoreMar 3, 2017
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A target to heal tiny lungs
The protein beta-catenin may be a good target for therapies to treat lung disease that is a common complication of preterm birth. Read MoreFeb 23, 2017
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Saliva test for obesity risk
“Epigenetic signatures” in DNA may present an opportunity for prevention of or early intervention in childhood obesity. Read MoreJan 24, 2017
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Single-cell analysis of solid tumors
A new method will make it possible to study solid tumors and healthy tissues using mass cytometry. Read MoreDec 12, 2016
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Growth hormone for Prader-Willi
Children with Prader-Willi Syndrome who received growth hormone treatment had cognitive advantages compared to untreated patients. Read MoreAug 25, 2016
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It takes two to tango: beta cell development
Defining the genes required for the function of insulin-producing beta cells is crucial for ongoing efforts to develop a cell-based therapy for diabetes. Read MoreJun 23, 2016
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Therapies to prevent preterm birth
Vanderbilt researchers have developed a high-throughput assay that will aid in identifying new compounds to treat preterm labor or postpartum bleeding. Read MoreFeb 9, 2016
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Preventing early pregnancy complications
The enzyme alkaline phosphatase may provide a new therapeutic option for women at high risk of pregnancy complications due to bacterial toxin exposure. Read MoreMay 20, 2015
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Staph ‘gangs’ share nutrients during infection: study
Antibiotic-resistant bacteria can share resources to cause chronic infections, Vanderbilt investigators have discovered. The findings shed light on a long-standing question in infectious diseases and may inform new treatment strategies. Read MoreOct 16, 2014
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Antibiotics, fetal vessel defect linked
Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis. Read MoreOct 15, 2014
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Antioxidants promising for rare disorder
The antioxidant vitamin E prevented the buildup of toxic products in a model of a rare genetic disorder, suggesting new strategies for therapeutic development. Read MoreFeb 6, 2014
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Pregnancy promoter and protector
Alkaline phosphatase enzymes appear to play roles in promoting pregnancy and in protecting the uterus from bacterial infection. Read MoreAug 23, 2013
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Oxidative stress in autism
A biomarker for oxidative stress is elevated in patients with both autism spectrum disorder and gastrointestinal dysfunction, suggesting opportunities for individualized approaches to clinical care. Read MoreAug 14, 2013
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Antacids: risky for premature babies
Antacids that block a certain enzyme pose a risk for a common cardiac problem in premature infants. Read MoreJun 12, 2013
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Factor reduces virus-related asthma attacks
An immune system factor associated with severe asthma may actually reduce asthma attacks induced by viral infections. Read MoreApr 26, 2013
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Fingers and toes: joint forming factor
The gene Has2 participates in signaling that is important in developing fingers and toes, and may have relevance for cancer development. Read MoreApr 1, 2013