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NICHD

Tailoring treatment for heart defect

Sep. 23, 2019—By defining the clinical and genetic factors that predict treatment response, Vanderbilt investigators aim to personalize therapy for a common heart complication in preterm infants.

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Microvilli in motion

Sep. 19, 2019—Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border.

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Indicators of despair rising among Gen X-ers entering middle age

Apr. 15, 2019—In 2016, a surprising decline in life expectancy was ascribed to "deaths of despair" among working-class middle-aged white men displaced by a changing economy. However, new research shows indicators of despair are rising among Americans approaching middle age regardless of race, education and gender.

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Analyzing single-cell landscapes

Nov. 30, 2018—Qi Liu, PhD, Ken Lau, PhD, and colleagues have developed a new tool, sc-UniFrac, to quantify diverse cell types in single-cell studies.

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Grant to help explore critical issues in Down syndrome

Oct. 26, 2018—A one-year $604,000 grant from the National Institute of Child Health and Human Development will allow researchers to to examine biological and phenotypic markers of Down syndrome.

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Grant to help explore critical issues in Down syndrome

Oct. 26, 2018—The grant will allow Kennedy Center researchers to analyze data from VUMC's Synthetic Derivative and BioVU databanks to study biomarkers associated with Down Syndrome.

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Investigators find that bile acids reduce cocaine reward

Aug. 30, 2018—The discovery that high levels of bile acids appear to blunt cravings for cocaine could lead to new treatments for addiction.

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Lung diseases share molecular signature

Apr. 5, 2018—Lung diseases of infancy and aging share a molecular signature, pointing to a potential target for treatment and prevention.

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Boys, girls reach activity levels in different ways

Mar. 15, 2018—Most preschool-age children manage to get enough recommended daily physical activity, but how they move varies with noticeable differences between boys and girls, a new Vanderbilt study found.

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Structure of a stem cell niche

Feb. 28, 2018—Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies.

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BOLD view of white matter

Jan. 12, 2018—Vanderbilt investigators have discovered that functional MRI detects neural activity in both gray and white matter in the brain, suggesting new ways to investigate diseases such as Alzheimer’s and multiple sclerosis.

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Obesity interventions: ideal dose?

Dec. 21, 2017—The optimal “dose” for behavioral interventions to treat childhood obesity are not clear, Vanderbilt researchers concluded after analyzing 133 clinical trial that occurred over the course of 17 years.

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