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NICHD Archives

Lung diseases share molecular signature

Apr. 5, 2018—Lung diseases of infancy and aging share a molecular signature, pointing to a potential target for treatment and prevention.

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Boys, girls reach activity levels in different ways

Mar. 15, 2018—Most preschool-age children manage to get enough recommended daily physical activity, but how they move varies with noticeable differences between boys and girls, a new Vanderbilt study found.

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Structure of a stem cell niche

Feb. 28, 2018—Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies.

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BOLD view of white matter

Jan. 12, 2018—Vanderbilt investigators have discovered that functional MRI detects neural activity in both gray and white matter in the brain, suggesting new ways to investigate diseases such as Alzheimer’s and multiple sclerosis.

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Obesity interventions: ideal dose?

Dec. 21, 2017—The optimal “dose” for behavioral interventions to treat childhood obesity are not clear, Vanderbilt researchers concluded after analyzing 133 clinical trial that occurred over the course of 17 years.

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Forming memories through CaMKII

Dec. 19, 2017—Vanderbilt researchers have identified an interaction between two proteins that play a role in learning and memory.

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NSAIDs, genetics and miscarriage

Sep. 20, 2017—A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage.

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NOTCH1 role in heart development

Jul. 3, 2017—The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition.

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Mutation raises heart block risk

Mar. 3, 2017—A newly identified genetic risk factor for heart block after surgery may help guide the course of postoperative care.

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A target to heal tiny lungs

Feb. 23, 2017—The protein beta-catenin may be a good target for therapies to treat lung disease that is a common complication of preterm birth.

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Saliva test for obesity risk

Jan. 24, 2017—“Epigenetic signatures” in DNA may present an opportunity for prevention of or early intervention in childhood obesity.

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Single-cell analysis of solid tumors

Dec. 12, 2016—A new method will make it possible to study solid tumors and healthy tissues using mass cytometry.

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