NICHD
-
High blood pressure genes improve heart surgery survival in children
Vanderbilt researchers have found that children with a genetic makeup that predicts high blood pressure as adults are more likely to survive congenital heart defect repair surgery. Read MoreMar 24, 2022
-
Invasive strep can defy zinc toxicity
Vanderbilt researchers find that invasive Group B Streptococcus strains, a significant risk to pregnant patients and infants, can grow in presence of toxic zinc levels. Read MoreFeb 28, 2022
-
Genetic ancestry and hypertension risk
Racial disparities in hypertension risk are due in part to genetic differences between ancestries, Vanderbilt investigators find in a study of participants in the Million Veteran Program. Read MoreApr 29, 2021
-
Preserving gut mucus architecture
A new method that keeps microbes and gut cells together will be useful for studies of complex host-microbe interactions and for analysis of clinical specimens. Read MoreOct 20, 2020
-
Fibroids and birth outcomes
Women with three or more uterine fibroids — non-cancerous growths — during pregnancy are more likely to have infants with reduced birthweight and may need additional surveillance. Read MoreSep 8, 2020
-
Reducing stress in parents of children with autism
Parents of children with autism spectrum disorders benefited from the addition of mindfulness-based stress reduction to parent-implemented behavioral interventions. Read MoreApr 21, 2020
-
Protein interactions and brain function
Roger Colbran and colleagues have discovered new molecular details about the function of an enzyme with a key role in shaping learning and memory. Read MoreFeb 20, 2020
-
A key to calcium signaling
Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles. Read MoreFeb 11, 2020
-
New tool probes gene regulation
Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation. Read MoreFeb 6, 2020
-
Tailoring treatment for heart defect
By defining the clinical and genetic factors that predict treatment response, Vanderbilt investigators aim to personalize therapy for a common heart complication in preterm infants. Read MoreSep 23, 2019
-
Microvilli in motion
Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border. Read MoreSep 19, 2019
-
Indicators of despair rising among Gen X-ers entering middle age
In 2016, a surprising decline in life expectancy was ascribed to "deaths of despair" among working-class middle-aged white men displaced by a changing economy. However, new research shows indicators of despair are rising among Americans approaching middle age regardless of race, education and gender. Read MoreApr 15, 2019
-
Analyzing single-cell landscapes
Qi Liu, PhD, Ken Lau, PhD, and colleagues have developed a new tool, sc-UniFrac, to quantify diverse cell types in single-cell studies. Read MoreNov 30, 2018
-
Grant to help explore critical issues in Down syndrome
A one-year $604,000 grant from the National Institute of Child Health and Human Development will allow researchers to to examine biological and phenotypic markers of Down syndrome. Read MoreOct 26, 2018
-
Grant to help explore critical issues in Down syndrome
The grant will allow Kennedy Center researchers to analyze data from VUMC's Synthetic Derivative and BioVU databanks to study biomarkers associated with Down Syndrome. Read MoreOct 26, 2018
-
Investigators find that bile acids reduce cocaine reward
The discovery that high levels of bile acids appear to blunt cravings for cocaine could lead to new treatments for addiction. Read MoreAug 30, 2018
-
Lung diseases share molecular signature
Lung diseases of infancy and aging share a molecular signature, pointing to a potential target for treatment and prevention. Read MoreApr 5, 2018
-
Boys, girls reach activity levels in different ways
Most preschool-age children manage to get enough recommended daily physical activity, but how they move varies with noticeable differences between boys and girls, a new Vanderbilt study found. Read MoreMar 15, 2018
-
Structure of a stem cell niche
Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies. Read MoreFeb 28, 2018
-
BOLD view of white matter
Vanderbilt investigators have discovered that functional MRI detects neural activity in both gray and white matter in the brain, suggesting new ways to investigate diseases such as Alzheimer’s and multiple sclerosis. Read MoreJan 12, 2018