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NIA Archives

Imaging guides Alzheimer gene search

Feb. 28, 2014—Using imaging data, Vanderbilt researchers discovered an association between a gene pair and brain changes in Alzheimer’s disease.

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Antioxidants promising for rare disorder

Feb. 6, 2014—The antioxidant vitamin E prevented the buildup of toxic products in a model of a rare genetic disorder, suggesting new strategies for therapeutic development.

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A pain in the … genes

Jan. 10, 2014—Vanderbilt researchers have discovered that variation in the gene encoding the potassium channel GIRK1 plays a role in modulating human pain perception.

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Cancer drug enhances cognition

Dec. 16, 2013—The breast cancer drug tamoxifen improves cognitive performance in post-menopausal women.

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Mitochondrial mutations not random

Nov. 25, 2013—A study of mitochondrial DNA mutations suggests they result from a process that selects for particular mutations in certain tissues.

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Amish aid study of Parkinson genetics

Nov. 11, 2013—Amish populations are valuable for genetic research because of their isolation, shared ancestry and homogeneous lifestyles.

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Metabolic profiling of vision loss

Sep. 27, 2013—A panel of metabolites – small molecules that are part of metabolic processes – that are unique to macular degeneration will shed light on the disease and aid diagnosis.

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Amish aid search for Alzheimer’s genes

Oct. 11, 2012—An analysis of Amish populations revealed novel risk genes for late-onset Alzheimer disease.

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Pathways to delirium in the ICU

Apr. 17, 2012—Study suggests that the “kynurenine” biochemical pathway could be a target for reducing delirium and coma in critically ill patients.

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Nicotine may aid memory for some older adults: study

Jan. 13, 2012—Wearing a nicotine patch may help improve memory loss in older adults with mild cognitive impairment, according to a study published this week by Paul Newhouse, director of the Center for Cognitive Medicine.

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