NIA

  • close up of mans arm as he receives chemotherapy infusion

    Mood and cognition after chemotherapy

    Validation of cognitive complaints appears to improve mood in patients with persistent chemotherapy-cognitive impairment, Vanderbilt researchers report. Read More

    Jul. 26, 2021

  • COVID ICU

    Delirium and mortality reexamined

    A multicenter study of ICU patients found that in the hospital, delirium was associated with a nearly three-fold increase in risk of death the following day, but after discharge there was no association between delirium and mortality. Read More

    Jul. 8, 2021

  • A caregiver talking to a wheelchair-bound patient

    A compound to counteract aging?

    A compound that increases lifespan in yeast is offering clues to pharmacological approaches that might slow the aging process and improve health. Read More

    Apr. 29, 2021

  • close up of mans arm as he receives chemotherapy infusion

    Chemo for cancer lowers dementia risk

    Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people. Read More

    Mar. 22, 2021

  • running jogging

    Strength training for osteoarthritis

    High-intensity strength training is not more effective than low-intensity training or educational efforts for reducing knee pain in patients with osteoarthritis. Read More

    Mar. 18, 2021

  • Vanderbilt University

    New clue to Alzheimer’s disease

    Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease. Read More

    Sep. 3, 2020

  • Close-up medical syringe drawing medication from a vial

    Genetic screen in worms reveals critical step in insulin synthesis

    The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes. Read More

    Dec. 4, 2019

  • Elderly woman looking out window

    Probing the pathology of impaired cognition

    A new link between a support protein within the brain's white matter and known Alzheimer's biomarkers discovered by Angela Jefferson and colleagues bring researchers a step toward earlier and more precise detection of neuropathology underlying cognitive impairment that may lead to new targeted therapies Read More

    Oct. 26, 2018

  • Vanderbilt University

    Alzheimer’s proteins in ICU survivors

    The cognitive impairment that affects patients who survive a stay in the ICU does not appear to have a similar mechanism to Alzheimer’s disease, Vanderbilt researchers have discovered. Read More

    Mar. 27, 2018

  • Vanderbilt University

    Vitamin C deficiency and mitochondrial dysfunction in Alzheimer’s disease

    Recent findings suggest that vitamin C deficiency could contribute to Alzheimer’s disease, suggesting that avoiding deficiency through diet and supplementation could protect against disease onset. Read More

    Dec. 1, 2017

  • Vanderbilt University

    Pain and Alzheimer’s disease

    Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked. Read More

    Sep. 5, 2017

  • Pediatric health conditions, their treatments and the related stress hinder the prefrontal cortex, which is the region of the brain associated with learning, memory and behavior. (istock)

    Oxidative stress on the brain

    Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders. Read More

    Aug. 23, 2017

  • lungs

    Clue to pulmonary hypertension

    Vanderbilt investigators have studied the relationship between race, cardiometabolic traits and pulmonary hypertension. Read More

    Apr. 13, 2017

  • Vanderbilt University

    A molecular clue to longevity

    In budding yeast, accumulation of a certain type of RNA in the nucleus increased life span, offering a new clue to longevity. Read More

    Mar. 31, 2017

  • Vanderbilt University

    Delirium in the ED

    Interventions for delirium in the emergency department setting are needed to preserve patients’ long-term function and cognition, Vanderbilt investigators have found. Read More

    Mar. 20, 2017

  • Vanderbilt University

    Dementia linked to diet

    Some memory deficits observed in Alzheimer’s disease may be due to co-morbid illnesses – not the disease itself – and may be reversed by lifestyle changes or pharmacologic interventions. Read More

    Feb. 7, 2017

  • Vanderbilt University

    Risk factors for delirium

    High levels of blood markers for vascular endothelial dysfunction were associated with longer periods of confusion in ICU patients, Vanderbilt researchers have discovered. Read More

    Sep. 13, 2016

  • Vanderbilt University

    Aging insights from budding yeast

    The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered. Read More

    Apr. 2, 2015

  • Vanderbilt University

    New target for breast cancer therapy

    The protein MTBP is overexpressed in an aggressive type of breast cancer, and it regulates another protein implicated in many cancer types, suggesting that it may be a good target for new therapeutics. Read More

    Jul. 31, 2014

  • Vanderbilt University

    Delirium increases long-term disability

    Patients who suffer a longer duration of delirium in the intensive care unit are more likely to experience long-term disability after discharge. Read More

    Mar. 17, 2014