NIA

The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered. Read More

The protein MTBP is overexpressed in an aggressive type of breast cancer, and it regulates another protein implicated in many cancer types, suggesting that it may be a good target for new therapeutics. Read More

Patients who suffer a longer duration of delirium in the intensive care unit are more likely to experience long-term disability after discharge. Read More

Using imaging data, Vanderbilt researchers discovered an association between a gene pair and brain changes in Alzheimer’s disease. Read More

The antioxidant vitamin E prevented the buildup of toxic products in a model of a rare genetic disorder, suggesting new strategies for therapeutic development. Read More

Vanderbilt researchers have discovered that variation in the gene encoding the potassium channel GIRK1 plays a role in modulating human pain perception. Read More

The breast cancer drug tamoxifen improves cognitive performance in post-menopausal women. Read More

A study of mitochondrial DNA mutations suggests they result from a process that selects for particular mutations in certain tissues. Read More

Amish populations are valuable for genetic research because of their isolation, shared ancestry and homogeneous lifestyles. Read More

A panel of metabolites – small molecules that are part of metabolic processes – that are unique to macular degeneration will shed light on the disease and aid diagnosis. Read More

An analysis of Amish populations revealed novel risk genes for late-onset Alzheimer disease. Read More

Study suggests that the “kynurenine” biochemical pathway could be a target for reducing delirium and coma in critically ill patients. Read More

Wearing a nicotine patch may help improve memory loss in older adults with mild cognitive impairment, according to a study published this week by Paul Newhouse, director of the Center for Cognitive Medicine. Read More