NIA
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VISE affiliate receives prestigious NIH award for her research on Alzheimer’s Disease
Biomedical engineering doctoral student Sarah Goodale has been awarded a National Institute on Aging Transition to Postdoc Fellowship for her proposed work on investigating fatigue and sleep disturbance symptoms in Alzheimer’s Disease and their relationship with functional and structural properties of the brain and intellectual decline. The National Institutes of Health NIA F99/K00 award supports... Read MoreNov 3, 2022
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PET imaging probe for Alzheimer’s disease
Vanderbilt researchers report on a new PET imaging probe that will be useful for exploring Alzheimer’s disease pathology. Read MoreFeb 24, 2022
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Ensuring the “best possible” medication history
About 80% of hospital admission electronic records were missing a drug prescribed to an older adult, Vanderbilt researchers found, highlighting the need for a multipronged approach to address medication discrepancies and support safe prescribing practices. Read MoreJan 18, 2022
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Mood and cognition after chemotherapy
Validation of cognitive complaints appears to improve mood in patients with persistent chemotherapy-cognitive impairment, Vanderbilt researchers report. Read MoreJul 26, 2021
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Delirium and mortality reexamined
A multicenter study of ICU patients found that in the hospital, delirium was associated with a nearly three-fold increase in risk of death the following day, but after discharge there was no association between delirium and mortality. Read MoreJul 8, 2021
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A compound to counteract aging?
A compound that increases lifespan in yeast is offering clues to pharmacological approaches that might slow the aging process and improve health. Read MoreApr 29, 2021
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Chemo for cancer lowers dementia risk
Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people. Read MoreMar 22, 2021
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Strength training for osteoarthritis
High-intensity strength training is not more effective than low-intensity training or educational efforts for reducing knee pain in patients with osteoarthritis. Read MoreMar 18, 2021
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New clue to Alzheimer’s disease
Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease. Read MoreSep 3, 2020
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Genetic screen in worms reveals critical step in insulin synthesis
The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes. Read MoreDec 4, 2019
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Probing the pathology of impaired cognition
A new link between a support protein within the brain's white matter and known Alzheimer's biomarkers discovered by Angela Jefferson and colleagues bring researchers a step toward earlier and more precise detection of neuropathology underlying cognitive impairment that may lead to new targeted therapies Read MoreOct 26, 2018
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Alzheimer’s proteins in ICU survivors
The cognitive impairment that affects patients who survive a stay in the ICU does not appear to have a similar mechanism to Alzheimer’s disease, Vanderbilt researchers have discovered. Read MoreMar 27, 2018
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Vitamin C deficiency and mitochondrial dysfunction in Alzheimer’s disease
Recent findings suggest that vitamin C deficiency could contribute to Alzheimer’s disease, suggesting that avoiding deficiency through diet and supplementation could protect against disease onset. Read MoreDec 1, 2017
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Pain and Alzheimer’s disease
Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked. Read MoreSep 5, 2017
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Oxidative stress on the brain
Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders. Read MoreAug 23, 2017
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Clue to pulmonary hypertension
Vanderbilt investigators have studied the relationship between race, cardiometabolic traits and pulmonary hypertension. Read MoreApr 13, 2017
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A molecular clue to longevity
In budding yeast, accumulation of a certain type of RNA in the nucleus increased life span, offering a new clue to longevity. Read MoreMar 31, 2017
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Delirium in the ED
Interventions for delirium in the emergency department setting are needed to preserve patients’ long-term function and cognition, Vanderbilt investigators have found. Read MoreMar 20, 2017
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Dementia linked to diet
Some memory deficits observed in Alzheimer’s disease may be due to co-morbid illnesses – not the disease itself – and may be reversed by lifestyle changes or pharmacologic interventions. Read MoreFeb 7, 2017
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Risk factors for delirium
High levels of blood markers for vascular endothelial dysfunction were associated with longer periods of confusion in ICU patients, Vanderbilt researchers have discovered. Read MoreSep 13, 2016