NHLBI
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Prenatal folic acid and asthma
The timing of folic acid-containing prescription filling during pregnancy was associated with childhood asthma, according to a new Vanderbilt study. Read MoreOct 30, 2015
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Risk of death in the ICU
The irregular heart rhythm atrial fibrillation increases the risk of death in patients in the intensive care unit. Read MoreOct 15, 2015
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Tolerating a transplant
A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease. Read MoreOct 1, 2015
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Heart repair factor
A signaling factor called Wnt10b is a novel target for optimizing cardiac repair after a heart attack. Read MoreSep 17, 2015
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Bridging the antibiotic gap
Vanderbilt researchers have discovered how certain molecules with antibiotic properties are synthesized, findings that could lead to new drugs that overcome the increased antibiotic resistance in bacteria. Read MoreAug 7, 2015
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Hhex on cancer
A new mouse model demonstrates that the Hhex gene – which is linked to blood cancers – is critical for normal blood cell production. Read MoreJul 13, 2015
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Delivering cells for heart repair
A polymer hydrogel material developed by Vanderbilt scientists improved the delivery of stem cells for heart repair. Read MoreJul 10, 2015
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Boosting cell-based heart repair
A metabolic change in adult stem cells makes them less “fit” for regenerative heart therapies, suggesting that strategies to prevent this response may boost the therapeutic usefulness of the cells. Read MoreMay 15, 2015
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New player in heart cell growth
Vanderbilt researchers have identified a new protein involved in heart cell growth, which could improve understanding of pathologic cardiac hypertrophy. Read MoreApr 6, 2015
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Contributors to coronavirus ‘fitness’
Understanding the role that host membrane modification plays in coronavirus replication is essential for developing novel approaches to block the viruses that cause SARS and MERS. Read MoreFeb 24, 2015
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Kidney disease impacts HDL function
Chronic kidney disease impairs the protective functions of HDL, Vanderbilt researchers report this month. Read MoreFeb 11, 2015
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Cognitive changes in ‘standing’ syndrome
Patients with orthostatic intolerance – problems when standing – have cognitive changes, even when seated, compared to healthy individuals. Read MoreJan 13, 2015
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Does fish oil help prevent A-fib?
Growing evidence suggests that fish oil, thought to directly prevent inflammation, oxidative stress and heart disease, may have limited clinical utility. Read MoreJan 9, 2015
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Atrial disease and hypertension links
New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease. Read MoreDec 18, 2014
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Target for atherosclerosis therapies
A newly identified “atheroprotective” gene is a tool for exploring plaque pathophysiology and may be a good target for therapies to slow atherosclerosis progression. Read MoreDec 17, 2014
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Protein implicated in atherosclerosis
Vanderbilt researchers have discovered a new target for the prevention of atherosclerotic plaque development and cardiovascular disease. Read MoreNov 25, 2014
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Overactive stress response in obesity
An overactive stress response contributes to the development of insulin resistance in obese individuals, and blocking it may be therapeutically beneficial. Read MoreNov 7, 2014
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Peptide quells “genomic storm”
A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection. Read MoreOct 28, 2014
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Immune cells’ role in hypertension
Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease. Read MoreOct 24, 2014
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Antibiotics, fetal vessel defect linked
Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis. Read MoreOct 15, 2014