NHLBI

Interventions for delirium in the emergency department setting are needed to preserve patients’ long-term function and cognition, Vanderbilt investigators have found. Read More

A newly identified genetic risk factor for heart block after surgery may help guide the course of postoperative care. Read More

“Epigenetic signatures” in DNA may present an opportunity for prevention of or early intervention in childhood obesity. Read More

Vanderbilt researchers have made the surprising discovery that the protease plasmin, known for its clot-busting role in the blood, protects soft tissue from turning to bone after severe injuries and certain orthopaedic surgeries. Read More

A compound found in buckwheat seeds extends the lifespan of worms, Vanderbilt investigators have discovered. Read More

Vanderbilt University Medical Center is part of a 6-year, $4.4 million grant from the National Institutes of Health to improve the use of prescribed medication by sickle cell patients. Read More

High levels of blood markers for vascular endothelial dysfunction were associated with longer periods of confusion in ICU patients, Vanderbilt researchers have discovered. Read More

A protein called Gremlin 2 controls the extent of inflammation after heart attack and may be a good therapeutic target. Read More

Increased activity of the “fight or flight” nervous system contributes to obesity-associated hypertension and may be a good therapeutic target for the disease. Read More

Vanderbilt University Medical Center (VUMC) has received an $11 million program project renewal grant from the National Heart, Lung and Blood Institute to study the genetics and underlying biological mechanisms that lead to idiopathic pulmonary fibrosis (IPF). Read More

A peptide molecule relaxes airway smooth muscle and may be a potential therapeutic for asthma that has become resistant to standard therapies. Read More

Cells from the bone marrow participate in the development of pulmonary arterial hypertension (PAH), and they can also protect against it, according to new findings from a team of Vanderbilt University Medical Center investigators. Read More

Long-acting opioids are associated with a significantly increased risk of death when compared with alternative medications for moderate-to-severe chronic pain, according to a Vanderbilt study released today in the Journal of the American Medical Assocation (JAMA). Read More

A new study finds that uninsured heart attack patients are more likely to be transferred. Read More

New findings identify isoketal-modified proteins as a previously unrecognized feature of pulmonary fibrosis and as a potential therapeutic target for this disease. Read More

Vanderbilt researchers have identified biomarkers that could be useful for evaluating and treating pregnancy-related heart failure. Read More

A newly discovered mechanism that helps cancer cells avoid destruction by immune system cells may improve immunotherapies. Read More

Signaling by a receptor that is overexpressed in aggressive forms of breast cancer has been linked to glutamine metabolism, suggesting new anti-cancer therapeutic targets. Read More

Vanderbilt researchers show that a certain factor negatively impacts the first-line responder cells in the lungs, providing one explanation for why patients with asthma are at greater risk for invasive bacterial disease. Read More

Using patients’ health records to assess preparedness for hospital discharge is more effective at predicting readmission or death than commonly used questionnaires. Read More