NHLBI

Structural features of newly formed HDL particles will help guide understanding of “good cholesterol” and its function. Read More

A protease gene family may be new targets for treating mitral valve disease, which causes blood to flow backwards in the heart. Read More

New research links nutrient-responsive cellular signaling to the antibody-mediated immune response. Read More

Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias. Read More

Lung diseases of infancy and aging share a molecular signature, pointing to a potential target for treatment and prevention. Read More

The cognitive impairment that affects patients who survive a stay in the ICU does not appear to have a similar mechanism to Alzheimer’s disease, Vanderbilt researchers have discovered. Read More

Most preschool-age children manage to get enough recommended daily physical activity, but how they move varies with noticeable differences between boys and girls, a new Vanderbilt study found. Read More

Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders. Read More

New findings suggest that oxidative stress damages mitochondrial DNA, and they link this damage to a disease state. Read More

Acetaminophen may offer a simple treatment to prevent tissue injury following lung transplant, Vanderbilt researchers have discovered. Read More

Vanderbilt investigators have discovered a role for immune system T cells in slowing the decline in skeletal muscle function in patients with Duchenne muscular dystrophy. Read More

Members of Vanderbilt Heart and Vascular Institute (VHVI) gathered for a photo last week to recognize National Wear Red Day. Read More

Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered. Read More

The optimal “dose” for behavioral interventions to treat childhood obesity are not clear, Vanderbilt researchers concluded after analyzing 133 clinical trial that occurred over the course of 17 years. Read More

To develop strategies for preventing radiation-induced lung fibrosis (scarring), Vanderbilt investigators are exploring the cell types and factors that contribute to the fibrotic response. Read More

Vanderbilt researchers have identified a pathway that links excess sodium, inflammation and hypertension. Read More

Based on findings from Vanderbilt investigators and others, clinical trials of estrogen inhibition for pulmonary arterial hypertension have recently been approved and funded by the National Institutes of Health. Read More

The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition. Read More

Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension. Read More

Vanderbilt investigators have studied the relationship between race, cardiometabolic traits and pulmonary hypertension. Read More