NCI

Vanderbilt and University of California investigators have discovered the “cell of origin” for pancreatic ductal adenocarcinoma, a finding that could lead to early detection methods and new treatments. Read More

Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer. Read More

Archived tissue samples are yielding new disease biomarkers. Read More

The machinery that builds the characteristic shape of epithelial cells suppresses breast cancer formation and metastasis in a mouse model. Read More

A new map of the developing gut of quail offers valuable tool for studying intestinal diseases. Read More

Antioxidants promote cell growth in a mouse model of prostate cancer, Vanderbilt researchers report in the journal PLoS ONE. The findings provide insight into the recent controversy regarding antioxidants and prostate cancer prevention. Read More

Study adds evidence for infectious agents’ role in sarcoidosis, an inflammatory condition that can lead to respiratory failure and death. Read More

A protein normally known to promote cell death found to encourage survival of blood forming cells. Read More

The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer. Read More

Two newly identified gene variants linked to breast cancer may aid in predicting disease risk and targeting screening and prevention strategies. Read More

Use of complementary and alternative medicine differs by race and socioeconomic factors, study reports. Read More

Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together. Read More

“Orphan” enzyme may play role in cancer growth, new research suggests. Read More

New therapeutic target for angiosarcoma – an aggressive, highly fatal tumor of the blood vessels – identified. Read More

The respiratory virus HMPV uses its fusion (F) protein – which interacts with cellular receptors called integrins – to bind to and enter target cells. Read More

A protein associated with aggressive breast cancers may also influence resistance of lung cancer to targeted therapies. Read More

Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease. Read More

Socioeconomic factors, African ancestry linked to risk for cancer-causing infection. Read More

Vanderbilt-Ingram Cancer Center researchers have identified how one of the genes most commonly mutated in lung cancer may promote such tumors. Read More

MicroRNA “regulatory networks” generated at Vanderbilt aid search for biomarkers and new drugs to treat glioblastoma, the most common and lethal primary brain tumor. Read More