NCI

Therapeutic nanoparticles may offer a powerful new way to image and treat cancer at the same time. Read More

Vanderbilt investigators have combined next-generation sequencing technologies and bioinformatics analyses to screen for genome-wide genetic mutations associated with drug resistance in a series of lung cancer cell lines. Read More

A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies. Read More

The nuclear receptor TR3 contributes to ovarian cancer cell death in response to platinum-based chemotherapy – and may be a good target for overcoming cell resistance to certain treatments. Read More

A noninvasive test can be used to identify the presence of Helicobacter pylori and evaluate its virulence, which will be useful in areas with high rates of H. pylori-associated gastric cancer. Read More

A motor protein that helps drive cell division may be a promising new target for cancer therapeutics. Read More

The new web application NetGestalt will allow investigators to simultaneously visualize different types of data for the same gene – such as mutation, expression and modification. Read More

Vanderbilt researchers have discovered new roles for a protein involved in cell death processes that are activated to prevent tumor-causing DNA mutations. Read More

Researchers are developing imaging methods to predict patient outcome early in the course of chemotherapy for breast cancer – to allow clinicians to adjust therapy for patients who are not responding. Read More

A factor produced by most malignant cells can both promote and inhibit tumor growth – an insight that is critical to using cancer drugs developed to block this factor. Read More

A high-salt diet worsens the carcinogenic effects of Helicobacter pylori, a bacterium that colonizes the stomachs of half of the world’s population. Read More

An antioxidant enzyme also functions as a tumor suppressor to limit cancer development in the esophagus. Read More

A team led by Vanderbilt University biomedical engineer Michael Miga, associate professor of Biomedical Engineering, Radiology and Radiological Sciences, and Neurological Surgery, has been awarded a five-year, $3.1 million grant from the National Cancer Institute to enhance image-guided surgery techniques for safely removing liver tumors. Read More

Diagnostic codes used for billing purposes effectively identify smokers in a general clinic population and can be used to adjust smoking status in genetic and epidemiologic studies. Read More

Understanding how bacteria become resistant to quinolone antibiotics could guide strategies for developing new antibacterial drugs. Read More

Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require. Read More

Vanderbilt researchers report that they have found a factor involved in the persistence of embryonic cells implicated in childhood liver cancer. Read More

The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development. Read More

The kidney can mediate its own repair through proliferation of resident immune system cells. Read More

Structural studies reveal a new framework for understanding a central player in DNA processing. Read More