Nature Communications

A team of Vanderbilt University chemists started decoding the total human molecular picture by examining 456 variations of one class of molecule, lipids. Read More

Treatment of anemia caused by chronic kidney disease or other diseases often requires repeated — and costly — injections or infusions of an artificial form of the hormone erythropoietin (EPO), which stimulates production of red blood cells. Read More

Less than 20 years after it was developed, a thin, resilient sheet of carbon atoms with remarkable properties known as graphene is transforming biomedical fields as far flung as tissue engineering, neuroprosthetics and drug discovery. Read More

Immunotherapy, which harnesses the power of the immune system, is one of the most promising forms of cancer therapy and has been shown to work well against some types of cancer. Read More

Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies. Read More

New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away. Read More

Vanderbilt investigators have identified an unexpected link between cell survival and the polarized delivery of proteins to the surface of mammary epithelial cells. Read More

A natural signaling molecule that activates cannabinoid receptors in the brain plays a critical role in stress-resilience — the ability to adapt to repeated and acute exposures to traumatic stress, according to researchers at Vanderbilt University Medical Center. Read More

Pseudomonas aeruginosa and Staphylococcus aureus — two pathogens that frequently co-infect the lungs of patients with cystic fibrosis — appear to cooperate with each other, Vanderbilt investigators have discovered. When pseudomonas is starved for metal by the host, it shuts down the production of factors that would normally kill staph, promoting a co-infection. Read More

Chronic obstructive pulmonary disease (COPD) is a common smoking-related lung illness and the third leading cause of death in the United States. Scientists have long believed that inhaling toxic gases and particles from tobacco smoke causes inflammation of the small airways in the lungs, leading to the development of COPD. Read More

Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy. Read More

A new surgical procedure could offer a simpler approach to achieve some of the same weight-loss and metabolic benefits associated with gastric bypass surgery, researchers at VUMC report. Read More

The keys to longevity have been a source of curiosity and the basis of many research studies for years, yet the mechanisms underlying a person’s ability to live a long life are still not fully understood. Read More

Vanderbilt University researchers have found a genetic mutation that causes pulmonary hypertension in cattle grazed at high altitude, and which leads to a life-threatening condition called brisket disease. Read More

Human cells are constructed in large part from proteins whose activity can be altered by the incorporation of oxygen in what are known as redox modifications. Read More

A method for taking ultrafast "sonograms" of materials undergoing phase transitions sheds new light on the dynamics of this important phenomenon in the world’s fastest phase-change material. Read More