National Institutes Of Health

A team including the Sanders lab developed a new methodology for finding small molecules associated with lipid rafts, an essential part of cell structure and regulation. Read More

Mikail Rubinov, assistant professor of biomedical engineering, computer science, psychiatry and psychology, has been awarded a four-year, $1.1 million grant from the National Institute of Mental Health to better understand the development and organization of brain networks, as well as their change in development and aging. Read More

Stressful events can rapidly modify how the brain responds to its environment and guides behaviors. These processes are relevant for neurotypical brain function and for the development of affective disorders and other psychiatric diseases, yet we have much to learn regarding the underlying molecular mechanisms. In this paper, researchers utilized pharmacologic, transgenic, and optogenetic tools to evaluate changes in brain function related to stress. Read More

By Aaron Conley Systems biology and the Lopez lab The history of hermeneutics started with Aristotle—parts comprise the whole. To understand the whole, we need to understand the parts. And to understand the parts, we need to understand them in the context of the whole. Carlos F. Lopez, associate… Read More

A new comprehensive data set featuring neural images from children ages 5, 7 and 9 has been made available for cross-disciplinary research purposes.  Read More

Vanderbilt researchers examine how to rapidly characterize the biological impact of genetic editing on bacteria for energy production, drug discovery and more. Est. reading time: 2.5 mins. Read More

Researchers discover how a protein may treat schizophrenia, including reversing working memory deficits, a hallmark of schizophrenia for which there is currently no treatment. Read More

By reproducing conditions under which malaria occurs in nature, the Zwiebel Lab finds that the deadly pathogens responsible for human malaria provide a specific adaptive advantage to disease-transmitting mosquitoes, explaining the persistence of this ancient disease. Est. reading time: 2 mins. Read More

Stephen Fesik’s discovery of a cancer-targeting molecule has been made freely accessible through opnMe for global researchers to advance research into cancer therapeutics. Read More

Vanderbilt researchers push research on ketamine’s role as a rapid antidepressant another step forward. This work opens avenues for new therapeutics for half of people for whom today’s antidepressants don’t work. Read More

Research from scientists at the School of Medicine Basic Sciences and the Salk Institute for Biological Studies shows that cells in the pancreas form new cell types to mitigate injury but are then susceptible to cancerous mutations. Read More

Carl Johnson, Cornelius Vanderbilt Professor of Biological Sciences and expert in biological clocks, identifies temporal component to COVID-19 viral shedding. Est. reading time: 2.5 mins. Read More

Therapeutic MK2i-NP blocks both inflammation and an unhealthy conversion of cells in blood vessels after cardiovascular procedures, reducing the need for further interventions—cutting costs and reducing risks. Est. reading time: 2.5 minutes. Read More

Nine startups established at Vanderbilt’s Center for Technology Transfer and Commercialization and the Wond’ry have been awarded more than $4.5 million in federal Small Business Innovation Research and Small Business Technology Transfer grants and matching funds from Launch Tennessee, with the goal of accelerating technology commercialization, innovation and job creation across the state. Read More

Steven Townsend, associate professor of chemistry, and Fang Yan, research professor of pediatrics and cell and development biology, have discovered how a sugar in human breast milk mitigates damage to the small intestines caused by chemotherapy-induced mucositis. Read More

Discovery shows that dopamine is not a reward molecule at all, calling for revision of textbook facts regarding the hormone’s role in the brain. Est. reading time: 3.5 mins. Read More

Even in the absence of brain activity, nerve cells can turn on gene expression that is important for antidepressant effects. This novel finding from Lisa Monteggia gives researchers a more fundamental understanding of the brain’s mechanistic function for better therapeutics. Est. reading time: 2.5 mins. Read More

MuSyC is a technique to help researchers devise new combinations of drugs. An open-source analysis tool, it holds the promise speed such discoveries around the world. Read More

Lisa Monteggia leads discovery of the gene responsible for ketamine’s long-term effects with implications for antidepressant therapeutics. Est. reading time: 2.5 mins. Read More

Exercise and movement may be a prescription to mitigate drug and alcohol seeking behavior due to its influence on the brain. Est. reading time: 3 mins. Read More