Myocardial Infarction

Vanderbilt researchers demonstrate that the polymer P188 has promise as a therapy to prevent reperfusion injury — the cellular damage that occurs when blood flow returns after an ischemic event like a heart attack. Read More

Immune cells that produce an anti-inflammatory factor are enriched in fat tissue around the heart and may be good targets to improve heart attack outcomes. Read More

A new study published by Vanderbilt mechanobiology researchers details a possible solution for fine-tuning inflammation and cellular activity in cardiac recovery – thanks to an antibody initially developed for rheumatoid arthritis.  Read More

A protein called Gremlin 2 controls the extent of inflammation after heart attack and may be a good therapeutic target. Read More

A polymer hydrogel material developed by Vanderbilt scientists improved the delivery of stem cells for heart repair. Read More

Reducing heart muscle response to calcium could decrease the risk of fatal arrhythmias after heart attacks. Read More

Managing myocardial infarction – and the resulting heart failure – remains a clinical challenge. To search for chemicals that can stimulate cardiac muscle cell production, Vanderbilt Institute of Chemical Biology investigators led by Tao Zhong, Ph.D., Terri Ni, Ph.D., and Eric Rellinger, M.D., turned to a novel drug discovery tool:… Read More

A certain signaling pathway could be key to improving cardiac repair after a heart attack. Read More