Molecular Physiology And Biophysics
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A cataract-heart connection
Studies of alpha-B crystallin in zebrafish could ultimately lead to improved treatment for cataracts and heart disease. Read MoreJan 25, 2018
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Study may point to new ways to reverse insulin resistance
Researchers at Vanderbilt University have discovered how insulin crosses the capillary endothelium to exit blood vessels and stimulate skeletal muscle cells — a major finding that may lead to new ways to reverse insulin resistance, a hallmark of type 2 diabetes. Read MoreJan 25, 2018
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Forming memories through CaMKII
Vanderbilt researchers have identified an interaction between two proteins that play a role in learning and memory. Read MoreDec 19, 2017
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Salt, inflammation and hypertension
Vanderbilt researchers have identified a pathway that links excess sodium, inflammation and hypertension. Read MoreNov 13, 2017
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How Epo action is ‘enhanced’
The hormone erythropoietin (Epo) controls red blood cell production and synthetic forms of Epo treat multiple disorders. New Vanderbilt research details how Epo works. Read MoreJul 24, 2017
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VU scientists report a way to calm the sepsis “storm”
Researchers at Vanderbilt University Medical Center (VUMC) have found a way to calm the “genomic storm” that triggers the often-lethal consequences of sepsis. Read MoreJun 22, 2017
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Grant bolsters Nakagawa’s research on autism, other brain disorders
Terunaga Nakagawa, M.D., Ph.D., associate professor of Molecular Physiology and Biophysics, has received a two-year, $100,000 grant from the Brain and Behavior Research Foundation to continue his studies of the molecular underpinnings of autism and other brain disorders. Read MoreApr 20, 2017
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Vanderbilt-led study shows high-salt diet decreases thirst, increases hunger
Salted peanuts make you thirsty so you drink more: that’s bartender wisdom. While that may be true in the short-term, within 24 hours increasing salt consumption actually makes you less thirsty because your body starts to conserve and produce water. Read MoreApr 18, 2017
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Study catches ‘notorious’ drug pump in action
Researchers at Vanderbilt University Medical Center (VUMC) have mapped the conformational changes that occur in a protein “notorious” for pumping chemotherapeutic drugs out of cancer cells and blocking medications from reaching the central nervous system. Read MoreMar 16, 2017
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Study to track diabetes drug’s ability to also treat asthma
Investigators in the Division of Allergy, Pulmonary, and Critical Care Medicine and the Division of Diabetes, Endocrinology, and Metabolism recently received a $1.25 million grant from the National Institute of Allergy and Infectious Diseases. Read MoreJan 19, 2017
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Probing drug abuse circuitry
Vanderbilt researchers have identified cocaine-induced modifications at specific neuronal connections, which could aid the development of new therapies for substance abuse disorders. Read MoreNov 4, 2016
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It takes two to tango: beta cell development
Defining the genes required for the function of insulin-producing beta cells is crucial for ongoing efforts to develop a cell-based therapy for diabetes. Read MoreJun 23, 2016
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Hasty selected to participate in academic medicine program for women
Alyssa Hasty, Ph.D., a Vanderbilt obesity researcher, has been selected to participate in the 22nd class of the Hedwig van Ameringen Executive Leadership in Academic Medicine Program for Women. Read MoreJun 9, 2016
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COX-2 blocker could help PTSD
COX-2 inhibitors – used clinically to reduce inflammation and pain – may find new applications for treating PTSD and other stress-related psychiatric disorders like major depression. Read MoreMay 12, 2016
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Study spots possible new approach to prevent obesity
An international research team that included scientists from Vanderbilt University Medical Center has found a novel way to counteract obesity in mice — by stimulating the growth of blood vessels in fat tissue. Read MoreApr 14, 2016
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Fat hormone’s role in zebrafish
The hormone leptin regulates glucose balance, but not fat stores, in zebrafish. Read MoreMar 8, 2016
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School of Medicine’s Patel receives Presidential Early Career Award
Vanderbilt University Medical Center’s Sachin Patel, associate professor of Psychiatry and of Molecular Physiology and Biophysics, is one of 106 researchers named today by President Obama as a recipient of the Presidential Early Career Award for Scientists and Engineers, the highest honor bestowed by the United States government on science and engineering professionals in the early stages of their independent research careers. Read MoreFeb 19, 2016
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Dynamics of a drug resistance transporter
Vanderbilt investigators are exploring the shape changes in a multidrug transporter to understand the mechanisms of antibacterial resistance. Read MoreFeb 5, 2016
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VUMC study may offer answers for treating depression in alcoholics
A study by researchers at Vanderbilt University Medical Center is offering a glimmer of hope to alcoholics who find it hard to remain sober because their abstinence is hounded by stubborn, difficult-to-treat depression. Read MoreFeb 1, 2016
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Award recognizes Niswender’s research achievements
Kevin Niswender, M.D., Ph.D., a physician-scientist at Vanderbilt University Medical Center whose work has helped advance understanding of diseases ranging from obesity to schizophrenia, is one of 10 recipients of the 2016 Harrington Scholar-Innovator Awards. Read MoreJan 28, 2016