Mitosis
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VU study reveals factor’s new role in cell division, migration
Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery. Read MoreOct 30, 2014
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Manager of mitotic stress
The protein CK1 delays cell division to avoid the generation of defects that drive tumorigenesis. Read MoreDec 13, 2013
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Motor protein revs up cell division
A motor protein that helps drive cell division may be a promising new target for cancer therapeutics. Read MoreJul 29, 2013
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Divvying up chromosomes
(Benedict Campbell/Wellcome Images) Mitosis, or the separation of chromosomes during cell division, is driven by dynamic interactions between the kinetochore region on chromosomes and string-like structures called microtubules. A number of proteins, including the enzyme Cdk1, regulate these interactions, but it is unclear what kinetochore components such enzymes work… Read MoreDec 16, 2011