Manuel Ascano

Infectious diseases pose a significant global health challenge, accounting for a substantial proportion of deaths worldwide, according to recent data from the World Health Organization. Vanderbilt’s Life Science Showcase: Advancing Innovation in Infectious Diseases held on July 18 emphasized the vital importance of advancing research and innovation to combat these persistent threats. Read More

Manuel Ascano, associate professor of biochemistry and pathology, microbiology and immunology, and Dr. Alissa Weaver, Cornelius Vanderbilt Chair and director of the Vanderbilt Center for Extracellular Vesicle Research, are one of nine U.S. research teams awarded funding from the National Science Foundation to more fully understand the potential biotechnological uses of RNA, ranging from crop disease protection to treatments that combat cancer. Read More

Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA. Read More

Researchers have developed a method to identify the primary interactions between incoming viral RNA genomes and host proteins. Read More

Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies. Read More

Ebola. Chikungunya. Influenza. What’s to be done about these headline-grabbing, debilitating, often lethal viruses? Read More