Jeffrey Conn
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Potential schizophrenia treatment, discovered at Vanderbilt and being developed by Neumora Therapeutics, entering Phase 1 clinical trial
In just over two years, a Vanderbilt-Neumora collaboration has led to the Phase 1 clinical trial of a treatment for schizophrenia spectrum disorders, which affect 3.7 million adults in the United States. This is the third chemical compound discovered at the Warren Center for Neuroscience Drug Discovery to reach Phase 1 clinical trials. Read MoreDec 4, 2023
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Study explores potential new class of antidepressants
Researchers at VUMC have taken a major step that could ultimately facilitate development of a new class of antidepressants which may relieve symptoms more rapidly and effectively and with fewer side effects than current medications. Read MoreNov 21, 2019
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Investigators eye new target for treating movement disorders
Blocking a nerve-cell receptor in part of the brain that coordinates movement could improve the treatment of Parkinson’s disease, dyskinesia and other movement disorders, researchers at Vanderbilt University have reported. Read MoreJan 18, 2018
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Vanderbilt signs licensing, research agreements to develop new approach to schizophrenia treatment
Under the terms of the licensing agreement, Lundbeck has exclusively licensed rights to compounds developed at Vanderbilt that act on a receptor in the brain that has been implicated in schizophrenia. Read MoreJan 8, 2018
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Vanderbilt researchers’ papers among those most cited
Eight current faculty members at Vanderbilt have made this year’s list of scientists whose papers have been cited most frequently by other researchers. Read MoreDec 7, 2017
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Award honors Conn’s mental health research contributions
P. Jeffrey Conn, Ph.D., founding director of the Vanderbilt Center for Neuroscience Drug Discovery, has won a 2017 Research & Hope Award from the Pharmaceutical Research and Manufacturers of America (PhRMA) for outstanding research in the area of mental health. Read MoreOct 12, 2017
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Researchers eye potential schizophrenia ‘switch’
Researchers at Vanderbilt University Medical Center have discovered a key mechanism that explains how compounds they’re developing can suppress schizophrenia-like symptoms without side effects in mice. Read MoreSep 15, 2016
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Compound developed at VUMC may delay Huntington’s disease
A compound developed by researchers at Vanderbilt University can improve early symptoms and delay progression of Huntington’s disease in a mouse model of the neurodegenerative disorder. Read MoreOct 29, 2015
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Five VUMC faculty members on list of most frequently cited researchers
Five current faculty members at Vanderbilt University Medical Center have made this year’s list of scientists whose papers have been cited most frequently by others. Read MoreOct 8, 2015
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Findings reveal new target in quest to ease schizophrenia
Vanderbilt University researchers have uncovered a surprising finding that could lead to the development of new, more effective therapies for schizophrenia, which affects more than 2 million Americans. Read MoreMay 7, 2015
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Grant spurs schizophrenia research
Vanderbilt University is partnering with the William K. Warren Foundation of Tulsa, Oklahoma, on research aimed at improving the treatment of schizophrenia and other forms of serious mental illness. Read MoreFeb 12, 2015
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Conn lands Javits Neuroscience Investigator award
Vanderbilt University’s P. Jeffrey Conn, Ph.D., has won a Javits Neuroscience Investigator Award from the National Institute of Neurological Disorders and Stroke for discoveries that could lead to new treatments for anxiety, schizophrenia and other brain disorders. Read MoreAug 7, 2014
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Hamm’s lasting impact commended at Flexner Discovery Lecture
Heidi Hamm, Ph.D. In their introductions of Heidi Hamm, Ph.D., prior to her Flexner Discovery Lecture last week, Susan Wente, Ph.D., and P. Jeffrey Conn, Ph.D., recounted how early encounters with her influenced their careers. For Wente, associate vice chancellor for… Read MoreJun 19, 2014
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‘Missing link’ may spur new brain disorder drugs
Researchers at the Scripps Research Institute in San Diego and Vanderbilt University have discovered a “missing link” in the structure of a transmembrane receptor that could lead to new treatments for autism, schizophrenia, Parkinson’s disease and Alzheimer’s disease. Read MoreMar 13, 2014
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AstraZeneca, VU collaborate to develop new treatments for major brain disorders
AstraZeneca and Vanderbilt University have signed a research collaboration agreement to identify candidate drugs aimed at treating psychosis and other neuropsychiatric symptoms associated with major brain diseases such as Alzheimer’s disease and schizophrenia. Read MoreJan 14, 2013
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Nobel in Chemistry reveals VU ties that bind
Several Vanderbilt researchers have collaborated with this year's Nobel Chemistry winners. Read MoreOct 18, 2012
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VU, Bristol-Myers to collaborate on Parkinson’s therapies
Vanderbilt University and Bristol-Myers Squibb have signed a collaboration agreement for the discovery, development and commercialization of novel therapies acting on the mGluR4 glutamate receptor, known as positive allosteric modulators, or PAMs, for the treatment of Parkinson’s disease. Read MoreSep 21, 2012
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Insights for neuroscience drug discovery
When discovering drugs for brain disorders, it’s important to test the candidates in multiple ways to avoid advancing those with restricted physiological effects. Read MoreJul 17, 2012
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Minds wide open: Neuroscience at Vanderbilt
Vanderbilt University has emerged as one of the nation’s leading academic centers in neuroscience. Read MoreApr 6, 2012
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Vanderbilt expanding research enterprise into Williamson County
With the addition of a new 18,000-square-foot laboratory to be located within the Cool Springs Life Sciences Center, Vanderbilt University is expanding its research enterprise into Williamson County. Read MoreMar 9, 2012