James Crowe Jr.
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Research lab honored by World Vaccine Congress
The laboratory of James Crowe Jr., MD, director of the Vanderbilt Vaccine Center, received the 2018 Vaccine Industry Excellence Award for Best Academic Research Team at the 18th World Vaccine Congress in Washington, DC, this week. Read MoreApr 12, 2018
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Hope for an RSV vaccine
Newly discovered features in an RSV protein may be useful for rational structure-based vaccine design. Read MoreFeb 23, 2018
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VUMC joins national effort to block global pandemics of potentially lethal viruses
The U.S. Defense Advanced Research Projects Agency (DARPA) has signed a five-year cooperative agreement worth up to $28 million with Vanderbilt University Medical Center (VUMC) to develop methods for preventing the global spread of viruses like chikungunya and Zika. Read MoreJan 11, 2018
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Crowe elected a fellow of the National Academy of Inventors
James Crowe Jr., MD, director of the Vanderbilt Vaccine Center at Vanderbilt University Medical Center (VUMC), has been named a fellow of the National Academy of Inventors (NAI). Read MoreDec 14, 2017
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Vanderbilt leads international effort to develop universal flu vaccine
Researchers at Vanderbilt University Medical Center are leading an international effort to develop a universal influenza vaccine that would protect everyone against all strains of the flu anywhere in the world. Read MoreOct 26, 2017
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The Human Vaccines Project, Vanderbilt and Illumina join forces to decode the human immunome
The Human Vaccines Project and Vanderbilt University Medical Center (VUMC) announced this week that they joined forces with Illumina Inc. to decipher the human immunome, the genetic underpinnings of the immune system. Read MoreApr 11, 2017
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Crowe’s pediatric immune response research lauded
James Crowe Jr., M.D., director of the Vanderbilt Vaccine Center, is the 2017-2018 recipient of the Samuel Rosenthal Prize for Excellence in Academic Pediatrics. Read MoreFeb 23, 2017
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Team isolates new antibodies that may aid RSV vaccine design
Researchers at Vanderbilt University Medical Center (VUMC) have taken another step toward developing a vaccine against respiratory syncytial virus (RSV), the major cause of life-threatening pneumonia in infants worldwide. Read MoreFeb 9, 2017
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Early study finds antibody that ‘neutralizes’ Zika virus
Researchers at Vanderbilt University Medical Center and Washington University School of Medicine in St. Louis have isolated a human monoclonal antibody that in a mouse model “markedly reduced” infection by the Zika virus. Read MoreNov 7, 2016
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Investigators create ‘Trojan Horse’ to fight Ebola
A multi-center research team including scientists from the Vanderbilt Vaccine Center has come up with a clever “Trojan Horse” strategy for thwarting the highly lethal Ebola virus. Read MoreSep 8, 2016
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Research team takes aim at Ebola virus ‘decoy protein’
Using an antibody generated at Vanderbilt University Medical Center that neutralizes the Ebola virus, researchers at the Scripps Research Institute in La Jolla, California, have determined the structure of a “decoy” protein that may enable the virus to evade detection by the immune system. Read MoreAug 11, 2016
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Vanderbilt and Human Vaccines Project launch initial studies to decode the human immune system
Researchers at Vanderbilt University Medical Center this month began recruiting volunteers to participate in a clinical trial aimed at decoding the human “immunome,” the genetic underpinnings of the immune system. Read MoreJun 21, 2016
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Potent HIV antibodies suggest new vaccine development approach
It’s been known for some time that the immune system can produce antibodies capable of “neutralizing” HIV, and stopping the AIDS-causing virus dead in its tracks. Read MoreApr 7, 2016
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Vanderbilt researchers identify potential antibody treatment for H7 avian flu
Researchers at Vanderbilt University Medical Center have isolated human antibodies against a type of bird flu that has killed more than 200 people in China since 2012 and which may pose a worldwide pandemic threat. Read MoreMar 7, 2016
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Antibodies may be ‘silver bullet’ for Ebola viruses
There may be a “silver bullet” for Ebola, a family of hemorrhagic viruses, one of which has killed more than 11,000 people in West Africa in the past two years. Read MoreJan 21, 2016
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Caucus explores crucial role of NIH research funding
James Crowe Jr., M.D., director of the Vanderbilt Vaccine Center, and Anthony Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), recently participated in a U.S. Senate National Institutes of Health (NIH) caucus briefing held in Washington, D.C., by Senate NIH caucus co-chairs Sens. Lindsey Graham (R-SC) and Dick Durbin (D-IL). Read MoreDec 3, 2015
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Two Ebola Survivors’ Blood Could Help Vanderbilt Researchers Find A Treatment
Vanderbilt researchers could be one step closer to finding a way to fight the deadly Ebola virus – thanks to two Ebola victims from Nigeria, who faced death and survived. Vanderbilt researchers developed a unique method of isolating potent Ebola-fighting antibodies from survivors’ blood and they believe these newest… Read MoreOct 19, 2015
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Survivors of Ebola outbreak take part in VUMC vaccine study
Two survivors of a 2014 Ebola outbreak in Nigeria visited Vanderbilt University Medical Center last week to share their experiences and participate in a study aimed at finding ways to treat the often-fatal infection. Read MoreSep 24, 2015
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Ebola symposium to feature Nigerian physicians
Three Nigerian physicians who survived Ebola virus disease in July 2014 after coming in direct contact with an Ebola-infected patient will speak at Vanderbilt University Medical Center next Wednesday, Sept. 16. Read MoreSep 10, 2015
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How to trick a wily virus
Vanderbilt investigators have discovered how human antibodies induced during testing of an experimental “bird flu” vaccine kill the virus. Read MoreJul 24, 2015