JAMA

A Vanderbilt-led study evaluating two investigational drugs to treat severe COVID-19 demonstrated that neither drug was effective. Read More

Rapidly administering IV fluids to critically ill adults undergoing emergency tracheal intubation does not significantly decrease chances of hypotension (low blood pressure) and cardiac arrest, a Vanderbilt University Medical Center-led study shows. Read More

There is strong evidence that the medication apixaban (Eliquis) is preferable to rivaroxaban (Xarelto) for stoke prevention in patients with atrial fibrillation (AF), with both reduced rates of severe bleeding complications as well as strokes, according to study published Dec. 21 in JAMA. Read More

Two devices for placing a breathing tube during critical illness had similar success rates for intubation on the first attempt, according to a study published Dec. 8 in JAMA. Read More

High-intensity strength training is not more effective than low-intensity training or educational efforts for reducing knee pain in patients with osteoarthritis. Read More

Findings from a national study published Nov. 9 in the Journal of the American Medical Association (JAMA) “do not support” the use of hydroxychloroquine for the treatment of adult patients hospitalized with COVID-19, the report concludes. Read More

An observational study using medical record information from nearly 50,000 U.S. military veterans sheds new light on which drugs are best for patients with Type 2 diabetes and one of its common complications, kidney disease. Read More

A clinical trial of an intervention for sepsis in patients in Zambia, led by Vanderbilt investigators, topped the list of 2017 trials featured by the website The Bottom Line. Read More

Physicians have been objecting to the high cost of the certification fees of the American Board of Medical Specialties (ABMS) member boards for many years, and a research letter published recently by the Journal of the American Medical Association (JAMA) shows that the revenue of these boards greatly exceeded expenditures in 2013. Read More

Faced with the negative quality-of-life effects from surgery and radiation treatments for prostate cancer, low risk patients may instead want to consider active surveillance with their physician, according to a study released Tuesday by the Journal of the American Medical Association (JAMA). Read More

Long-acting opioids are associated with a significantly increased risk of death when compared with alternative medications for moderate-to-severe chronic pain, according to a Vanderbilt study released today in the Journal of the American Medical Assocation (JAMA). Read More

Among doctors, it is widely believed that a class of drugs called statins, which are used to lower cholesterol, might help patients tolerate the stress of cardiac surgery. Not so, according to a five-year, placebo-controlled, double-blinded randomized clinical trial conducted at Vanderbilt University Medical Center, published today in the… Read More

A genetic test that suggests a patient may be at increased risk for potentially fatal heart rhythms is very often not as ominous as it sounds. Read More

While 12 million Americans are enrolled in health care networks through the Affordable Care Act’s (ACA) insurance marketplace, a recent study in the Journal of the American Medical Association (JAMA) raises concerns about patient access to specialists within these insurance plans. Read More

Data in sports concussion studies will continue to be disputed as long as the injuries are diagnosed by differing standards instead of universal guidelines, a Vanderbilt investigator concludes in a recent review. Read More

A new study finds that a cognitive-behavioral prevention program yielded sustained positive effects for youth at risk for depression. Read More

More than half of hospitalizations due to influenza pneumonia could be prevented by influenza vaccination, according to a study led by investigators at Vanderbilt University Medical Center, published this week in the Journal of the American Medical Association. Read More

Vanderbilt University Medical Center researchers have found that bathing critically ill patients with disposable chlorhexidine cloths did not decrease the incidence of health care-associated infections when compared to less expensive nonantimicrobial cloths, according to a study appearing online in JAMA this week. Read More

Far more breast cancer patients are choosing to undergo mastectomy, including removal of both breasts, instead of choosing breast conservation surgery even when they have early stage disease that is confined to one breast, a Vanderbilt study shows. In the past decade, there have also been… Read More

A new analysis of published studies found that FDG-PET technology is less accurate in diagnosing lung cancer versus benign disease in regions where infections like histoplasmosis or tuberculosis are common. Read More