inflammatory bowel disease
Jul. 20, 2018—Disruption of the integrity of the intestinal lining or epithelium contributes to a “leaky” gut and is a common feature of patients with inflammatory bowel disease. Yash Choksi, Christopher Williams and colleagues found that low levels of a certain protein exacerbated the condition.
Feb. 1, 2017—Vanderbilt researchers have developed a new optical sensor that can accurately detect different types of inflammatory bowel disease and can be easily integrated into routine colonoscopy exams.
Oct. 13, 2016—Researchers at Vanderbilt University School of Medicine have uncovered a link between epidermal growth factor receptor (EGFR) signaling and the inflammatory response to bacterial infection in the gastrointestinal tract.
Jul. 23, 2015—An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.
Apr. 25, 2014—Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation.