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immune system Archives

Mom may pass bacteria to baby in utero: Study

Jul. 5, 2018—New findings by Jörn-Hendrik Weitkamp and colleagues provide the first account of bacterial signatures in mammalian fetal intestinal tissue. The results suggest that bacterial DNA moves from the mother’s microbiome into the fetal intestine, which may be a critical stimulus for normal mucosal immune development.

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Disease-fighting antibody production

Apr. 20, 2018—New research links nutrient-responsive cellular signaling to the antibody-mediated immune response.

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Muscular dystrophy clue

Feb. 9, 2018—Vanderbilt investigators have discovered a role for immune system T cells in slowing the decline in skeletal muscle function in patients with Duchenne muscular dystrophy.

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Researcher targets peanut allergies with Cohen Fund support

Oct. 12, 2017—Scott Smith, M.D., Ph.D., assistant professor of Medicine, has received a 2017 research award from the Stanley Cohen Innovation Fund to test a new therapeutic strategy for peanut allergies. Smith's research could fundamentally change allergy treatment.

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An immune regulator of addiction

Aug. 4, 2017—Although drug addiction is classically studied in a neuron-centric way, Vanderbilt researchers have discovered that the immune system also plays a critical role.

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HDAC3 role in B-cell development

Aug. 3, 2017—The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies.

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Pathology of septic shock

Feb. 8, 2017—The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection.

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New target for chronic infection

Feb. 2, 2017—An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered.

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Stem cells promote tolerance

Nov. 17, 2016—Blood-forming stem cells play a role in immune tolerance and acceptance of organ transplants, Vanderbilt researchers have discovered.

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Madhur lands NIH New Innovator Award

Oct. 6, 2016—Meena Madhur, M.D., Ph.D., assistant professor of Medicine, has received an NIH New Innovator Award, which is designed to support exceptionally creative, early-career investigators who propose innovative, high-impact projects.

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Vanderbilt and Human Vaccines Project launch initial studies to decode the human immune system

Jun. 21, 2016—Researchers at Vanderbilt University Medical Center this month began recruiting volunteers to participate in a clinical trial aimed at decoding the human “immunome,” the genetic underpinnings of the immune system.

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Immune defenses in asthma

Apr. 5, 2016—Vanderbilt researchers show that a certain factor negatively impacts the first-line responder cells in the lungs, providing one explanation for why patients with asthma are at greater risk for invasive bacterial disease.

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