Ian Macara
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Shedding light on a decades-old protein sorting mystery
Christian de Caestecker, a Ph.D. student in the lab of Ian Macara, Louise B. McGavock Professor and chair of the Department of Cell and Developmental Biology, has proposed and validated a mechanism that addresses a decades-old mystery surrounding epithelial cells. Read MoreSep 26, 2024
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Vanderbilt invests in research space to bolster faculty productivity
Construction projects represent more than $50 million of direct investment by the Office of the Provost and the Division of Administration to facilitate trans-institutional research and collaboration. Read MoreFeb 8, 2024
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Watch: ‘Scientist-Artists: Embracing Duality’ virtual event
Join Kendra Oliver, assistant professor of pharmacology and director and founder of ArtLab, for the next Lab-to-Table Conversation on Wednesday, July 27. The panelists will explore how a group of self-identified scientist-artists are embracing this particular duality. Read MoreJul 20, 2022
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Academic experts across disciplines tackle questions surrounding the origins of life
The School of Medicine Basic Sciences brought together a biologist, a Christian theologist, a philosopher and an astrophysicist June 17 for a lab-to-table conversation exploring their views and academic perspectives on the origins of life. Read MoreJul 7, 2021
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Discussion on the origins of life featuring cross-section of Vanderbilt academics set for June 17
How do academics with diverse areas of expertise view the origins of life? A June 17 virtual discussion hosted by the School of Medicine Basic Sciences will bring together perspectives from single-cell biology, theology, space and time and metaphysical philosophy to explore the unique and common understandings among the fields. Read MoreJun 3, 2021
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Vanderbilt postdoctoral fellows recognized at 2021 Spring Postdoc Awards
The Vanderbilt Postdoctoral Association and Office of Postdoctoral Affairs announced its 2021 award winners May 24. Postdoctoral fellows, commonly known as postdocs, are professionals who have earned doctoral degrees and are, in most cases, temporarily pursuing additional scholarly training, experience and research progress necessary for a wide range of career paths. Read MoreMay 25, 2021
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New CRISPR screening technique developed at Vanderbilt leads to discovery of pathway that may be linked to cancer initiation
A new genome-wide CRISPR screening technique conducted by researchers at Vanderbilt University is offering new insights about how tumors in 80 to 90 percent of all cancers grow. Read MoreMar 10, 2021
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Vanderbilt researchers make counterintuitive discoveries about immune-like characteristics of cells, chemotherapy’s impact on tissue growth
Biologists reveal that tissue perturbations by chemotherapy agents promote stem cell expansion and that fibroblast cells exhibit unexpected, immune-like behavior. Read MoreOct 15, 2020
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International collaboration with Vanderbilt scientists sheds light on rare exocyst mutations that cause severe developmental disabilities in children
Mukhtar Ahmed, Christian de Caestecker and Ian Macara, in collaboration with geneticists from Australia and Italy discover novel mutations in the Exocyst, providing new understanding of a critical cellular protein complex. Read MoreSep 14, 2020
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Wente and Macara named American Society for Cell Biology Fellows
Interim Chancellor and Provost Susan R. Wente and Louise B. McGavock Professor of Cell and Developmental Biology Ian Macara have been elected 2019 fellows of the American Society for Cell Biology. Read MoreOct 10, 2019
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The exocyst dynamo
Mukhtar Ahmed and colleagues say the methods they employed to understand the mechanisms by which exocysts--protein complexes essential to life--function have the potential to revolutionize our understanding of cell dynamics. Read MoreDec 14, 2018
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Macara named ‘Pink Tie Guy’ for Komen breast cancer research
Ian Macara, PhD, Louise B. McGavock Professor and Chair of Cell and Developmental Biology and co-leader of the Signal Transduction and Chemical Biology Research Program at Vanderbilt-Ingram Cancer Center (VICC), has been named one of the Pink Tie Guys for the Susan G. Komen Central Tennessee organization. Read MoreJan 11, 2018
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15 faculty members elected as AAAS fellows
Fifteen Vanderbilt faculty members conducting a range of biomedical and clinical research have been elected fellows of the American Association for the Advancement of Science. Six of the 15 have received funding through the university’s Trans-Institutional Programs initiative, which facilitates research and teaching collaborations across disciplines and are a core pillar of the university’s Academic Strategic Plan. Read MoreNov 20, 2017
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Talking epigenetics
Ian Macara, Ph.D., left, chair of the Department of Cell and Developmental Biology, and Lawrence Marnett, Ph.D., right, dean of Basic Sciences in the School of Medicine, visited with Rockefeller University professor David Allis, Ph.D., last week prior to Allis’ Flexner Discovery Lecture on epigenetics. Read MoreSep 14, 2017
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Polarity protein role in cell survival
Vanderbilt investigators have identified an unexpected link between cell survival and the polarized delivery of proteins to the surface of mammary epithelial cells. Read MoreApr 27, 2017
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Basic science, extraordinary impact
The discoveries that can change the course of human health forever often begin in the tiniest places: in molecules and cells, at the most fundamental intersection of physics, chemistry and biology. Understanding how these cellular and molecular processes work is the focus of basic biomedical research at Vanderbilt. Read MoreOct 6, 2016
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Breast cancer: finding the smoking gun
A new method developed at Vanderbilt may help “inventory” all tumor-promoting genes. Read MoreJul 20, 2016
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Macara lands award to explore cancer cell behavior
Vanderbilt’s Ian Macara, Ph.D., has won an Outstanding Investigator Award from the National Cancer Institute (NCI) — nearly $6.6 million over seven years — to support the “unusual potential” of his research, which seeks to understand and predict cancer cell “behavior.” Read MoreAug 13, 2015
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Worldwide Cancer Research lauds Macara’s contributions
Ian Macara, Ph.D., professor and chair of the Department of Cell and Developmental Biology, recently returned from Scotland, where he received this year’s Colin Thomson Memorial Medal for his contributions to cancer research. Read MoreJul 30, 2015
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Breast tissue growth protein may promote cancer: study
A protein essential for growth of normal breast tissue also may play a role in breast cancer, Vanderbilt University researchers have found. Read MoreJul 17, 2014