HSP
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Paraplegia-causing proteins pair up
Peter Hedera, M.D. Hereditary spastic paraplegia (HSP), a group of progressive neurodegenerative disorders that impairs the ability to walk, can be caused by mutations in more than 40 different genes. Despite this genetic heterogeneity, the pathologic features – degeneration of long axons in the spinal cord – are relatively uniform,… Read MoreFeb 4, 2011