Health And Medicine
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Research Staff Awards honor those who help drive engines of discovery
Laboratory and administrative personnel at Vanderbilt University Medical Center were honored last week for research excellence during the 17th annual Research Staff Awards, held virtually this year because of the pandemic. Read MoreFeb 18, 2021
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VUMC postdoctoral scientist named HHMI Hanna Gray Fellow
Valeria Reyes Ruiz, PhD, a postdoctoral fellow in the Department of Pathology, Microbiology and Immunology, has been selected as a 2020 Hanna Gray Fellow by the Howard Hughes Medical Institute (HHMI). Read MoreFeb 18, 2021
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Vanderbilt, Zambia researchers find delirium in hospitalized patients linked to mortality, disability in Sub-Saharan Africa
Delirium, a form of acute brain dysfunction, is widespread in critically ill patients in lower resourced hospitals, and the duration of delirium predicted both mortality and disability at six months after discharge, according to a study published in PLOS ONE. Read MoreFeb 11, 2021
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Grant supports speedy sorting of health records by phenotype
Wei-Qi Wei, MD, PhD, assistant professor of Biomedical Informatics and scientific director of the Precision Phenotyping Core at the Center for Precision Medicine, has been awarded a four-year, $1.7 million grant from the National Institutes of Health to continue development of high-throughput software for quickly identifying traits of interest, or phenotypes, in electronic health records (EHRs). Read MoreFeb 11, 2021
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Study will delve into EHR for signs of suicidality
Retrieval of clearer, more complete information from the EHR could go a long way toward improving predictive models of who will next be at risk of suicide, thereby improving care for patients with suicidal thoughts and behaviors. Read MoreFeb 11, 2021
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Imaging guidance for nerve repair
A noninvasive, quantitative MRI method could be used after surgical repair of traumatic peripheral nerve injury to help clinicians make decisions about whether additional surgical interventions are needed. Read MoreFeb 9, 2021
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Key factors in HIV-1 replication
HIV-1, the virus that causes AIDS, exploits inositol phosphates in T cells to aid its own assembly and maturation — suggesting that targeting inositol phosphate binding could inhibit HIV-1 replication. Read MoreFeb 8, 2021
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New clue to postural tachycardia
Insight into the pathophysiology of an enigmatic and debilitating disease suggests new treatment approaches. Read MoreFeb 4, 2021
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Potential biomarker for IBD severity, cancer risk identified
A selenium transport protein produced in the colon may be a novel biomarker for assessing disease severity and cancer risk in patients with inflammatory bowel disease. Read MoreFeb 4, 2021
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Gene network for leukemia factor
A new method speeds the analysis of factors that control gene expression from days to minutes, allowing researchers to uncover new targets for cancer treatment. Read MoreFeb 4, 2021
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Study finds recommended ICU sedatives equally safe, effective
Sedative medications used in intensive care are associated with increased delirium, which is in turn connected with higher medical costs and greater risk of death and ICU-related dementia. Read MoreFeb 2, 2021
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Study’s findings may help eventually close the door on COVID-19
Researchers at Vanderbilt University Medical Center and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles’ heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly head off future pandemics. Read MoreJan 28, 2021
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Study shows healthy diet is associated with diverse and health-promoting microbiome
Scientists are just beginning to understand the impact of diet on the gut microbiome and how this interaction affects human health, but baselines must first be established to yield answers. Read MoreJan 27, 2021
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Rare tumor disguised as benign
A rare tumor that causes facial weakness was found masquerading as a more common benign facial tumor. Read MoreJan 26, 2021
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An interacting factor in leukemia
A blood stem cell protein plays a role in the initiation and progression of leukemia, Vanderbilt researchers have found. Read MoreJan 25, 2021
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Inflammation in genetic epilepsy
Brain inflammation links genetic and acquired epilepsy — providing new clues about epilepsy development and pointing to potential treatments. Read MoreJan 21, 2021
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WIN for blocking cancer growth
William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth. Read MoreJan 21, 2021
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Mitochondrial stress and hypertension
Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential. Read MoreJan 12, 2021
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Microbial RNA and rheumatoid arthritis
Small RNAs — short stretches of genetic material — from microbes may be playing a role in rheumatoid arthritis and other autoimmune diseases. Read MoreJan 11, 2021
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Vitamin D activation and cancer risk
Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women. Read MoreJan 7, 2021