Health and Medicine

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Transporter mutation alters cell energy

Feb. 20, 2020—A disease-associated mutation in a transporter protein causes cells to increase energy production, as if they are starving, Vanderbilt researchers have discovered.

Vanderbilt University Medical Center among top 100 proposals for MacArthur Foundation $100 million grant

Feb. 19, 2020—The John D. and Catherine T. MacArthur Foundation today unveiled a grant proposal from Vanderbilt University Medical Center (VUMC) as one of the highest-scoring proposals, designated as the “Top 100,” in its 100&Change competition for a single $100 million grant to help solve one of the world’s most critical societal challenges.

Barbershops targeted to improve health of black men

Feb. 18, 2020—Black men with high blood pressure could benefit from a research study beginning this month to check their vitals while they are getting a haircut at a barbershop.

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Algorithm helps improve coronary calcium detection

Feb. 13, 2020—A new algorithm for artificial intelligence-assisted calcium scoring can accurately determine cardiovascular risk across a range of CT scans and in a racially diverse population.

A key to calcium signaling

Feb. 11, 2020—Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles.

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Imaging breast cancer cell size

Feb. 10, 2020—A noninvasive MRI approach assesses breast tumor cell size and could be a useful way to evaluate early response to neoadjuvant therapy.

Helicobacter Pylori bacterium, medical illustration pathogenic microorganism in human stomach

Powering H. pylori pathogenesis

Feb. 6, 2020—Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer.

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Antibody mixture may help block Ebola virus infection

Feb. 6, 2020—A research team led by scientists at Vanderbilt University Medical Center has developed an antibody mixture that in animals is highly effective in blocking infection by the Ebola virus.

Conn, Calipari to receive major pharmacology awards

Feb. 6, 2020—Two Vanderbilt University pharmacologists have won prestigious awards from the American Society for Pharmacology and Experimental Therapeutics (ASPET).

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Team tracks integrin’s role in lung function

Feb. 6, 2020—Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at VUMC have discovered.

Genomic analysis visualization. Dna genomes sequencing, deoxyribonucleic acid genetic map and genome sequence analyse. Bioinformatics forensics data or dna radiographic testing vector concept (Genomic analysis visualization

New tool probes gene regulation

Feb. 6, 2020—Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation.

Illustration: Acute lymphoblastic leukemia

Protein research seeks to induce tumor regression

Jan. 29, 2020—MYC is a family of three related proteins that are overexpressed in cancer and which contribute to an estimated 100,000 cancer deaths annually in the United States. Understanding how MYC works could lead to the development of new drugs that can effectively block MYC and stop many cancers in their tracks.