H. Pylori

H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered. Read More

The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate. Read More

Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer. Read More

New research findings provide insight into the detrimental events that develop in response to H. pylori infection. Read More

The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells. Read More

An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered. Read More

Vanderbilt researchers have discovered a link between Helicobacter pylori infection, inflammation and gastric cancer that could suggest new anti-cancer therapies. Read More

Researchers at Vanderbilt University School of Medicine have uncovered a link between epidermal growth factor receptor (EGFR) signaling and the inflammatory response to bacterial infection in the gastrointestinal tract. Read More

The bacterium Helicobacter pylori has been linked to anemia and may be contributing to the incidence and severity of anemia worldwide. Read More

Understanding how zinc and the host’s immune response control H. pylori’s cancer-causing potential could suggest new therapeutic strategies to reduce infection and cancer risk. Read More

by Denise Anthony (iStock) A Vanderbilt University-led research team has solved a long-standing riddle: Why do people of mostly Amerindian ancestry in the Andes have a gastric cancer rate that is 25 times higher than that of fellow Colombians of mostly African descent only 124 miles away on the coast?… Read More

Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer. Read More

A noninvasive test can be used to identify the presence of Helicobacter pylori and evaluate its virulence, which will be useful in areas with high rates of H. pylori-associated gastric cancer. Read More

A high-salt diet worsens the carcinogenic effects of Helicobacter pylori, a bacterium that colonizes the stomachs of half of the world’s population. Read More

Gastric cancer is the second leading cause of cancer death worldwide, with a particular burden in Latin America and eastern Asia. Read More

The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer. Read More

Socioeconomic factors, African ancestry linked to risk for cancer-causing infection. Read More

Treating H. pylori infection in children may help their growth rebound, a recent study suggests. Read More

Helicobacter pylori, a bacterium that infects half of the world’s population and increases the risk for stomach cancer, appears to impair nutrient absorption. Read More