GABA
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Team discovers one more piece to the autism puzzle
Vanderbilt investigators have linked genetic mutations in a single receptor to epilepsy, autism and intellectual disability. Read MoreOct 3, 2019
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Heat a trigger for seizures
Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation. Read MoreSep 6, 2017
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Protein structure and epilepsy severity
Understanding how mutations affect the structure and function of inhibitory neurotransmitter receptors will shed light on the mechanisms underlying some types of epilepsy. Read MoreNov 10, 2016
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Culprits in genetic epilepsies
Genetic variation in GABA-A receptors confers risk for inherited forms of epilepsy. Read MoreOct 11, 2016
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Seizure mutation impairs receptor
Defects in the production of certain receptors are linked to the pathogenesis of genetic epilepsies and fever-induced seizures. Read MoreSep 30, 2014
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Neuronal subtypes in genetic disorder
Inhibitory neurons that connect and regulate signaling in the brain (interneurons) may contribute to epilepsy and autism in patients with tuberous sclerosis complex. Read MoreSep 6, 2012
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Probing epilepsy’s molecular sparks
Understanding how mutations in neuronal receptors contribute to epilepsy could lead to improved therapies. Read MoreMay 10, 2012
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New laser technique opens doors for drug discovery
A new laser technique can measure interactions between proteins tangled in a cell's membrane and a variety of other biological molecules: extremely difficult measurements that can aid the process of drug discovery. Read MoreMar 14, 2011