G Protein-coupled Receptors

Vanderbilt researchers have uncovered a potential new way to help curb the rapidly rising worldwide prevalence of metabolic disorders, including obesity and diabetes. Read More

A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy. Read More

Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist. Read More

Thanks in part to a computer program named “Rosetta,” Vanderbilt University researchers are closer to understanding how the ubiquitous G protein is activated – a discovery that could lead to the design of more specific and effective drugs. Read More

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development. Read More

Heidi Hamm, Ph.D., chair of the Department of Pharmacology, has won the 2012 Ariens Award from the Dutch Pharmacological Society. Read More

Several Vanderbilt researchers have collaborated with this year's Nobel Chemistry winners. Read More