Epithelial
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Microvilli in motion
Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border. Read MoreSep 19, 2019
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Cell skeleton and the brush border
Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines. Read MoreJan 31, 2018
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Polarity protein suppresses tumor growth, invasion
The machinery that builds the characteristic shape of epithelial cells suppresses breast cancer formation and metastasis in a mouse model. Read MoreNov 29, 2012
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Intestinal artillery launches anti-bacterial attack
The epithelial cells that line the intestines have a newly discovered mechanism for protecting us against microbes: they fire anti-bacterial "bullets" into the gut. Read MoreMay 14, 2012
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Protein combos keep cells straight
Researchers define the protein interactions that establish our organs' lining. Read MoreMar 18, 2011