epilepsy Archives
Research reveals underappreciated role of brainstem in epilepsy
May. 31, 2018—New research from Vanderbilt suggests that repeated seizures reduce brainstem connectivity, a possible contributor to unexplained neurocognitive problems in epilepsy patients.
Cannabis compound reduces seizures
Feb. 26, 2018—Cannabidiol (CBD) oils reduced seizures in patients with difficult-to-treat epilepsy, Vanderbilt investigators have found.
Neurostimulation an option for some epilepsy patients
Sep. 28, 2017—Patients with epilepsy who suffer seizures that can’t be effectively treated with medications or established surgical interventions could benefit from responsive neurostimulation, a relatively new treatment.
Goal of new tissue-chip research is to assess efficacy of novel epilepsy drugs
Sep. 20, 2017—An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an “organ-on-chip” model for two genetic forms of epilepsy.
Heat a trigger for seizures
Sep. 6, 2017—Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation.
Predicting brain surgery outcomes
Aug. 18, 2017—Assessing brain functional and structural connectivity in patients with temporal lobe epilepsy may be a useful way to identify the best candidates for surgical treatment.
New clues emerge in rare form of childhood epilepsy
Dec. 15, 2016—Researchers at Vanderbilt University Medical Center (VUMC) are one step closer to understanding what causes early-onset epileptic encephalopathy, a rare form of childhood epilepsy that is difficult to treat and has poor developmental outcomes.
Protein structure and epilepsy severity
Nov. 10, 2016—Understanding how mutations affect the structure and function of inhibitory neurotransmitter receptors will shed light on the mechanisms underlying some types of epilepsy.
Culprits in genetic epilepsies
Oct. 11, 2016—Genetic variation in GABA-A receptors confers risk for inherited forms of epilepsy.
NIH grant boosts Englot’s epilepsy research efforts
Aug. 4, 2016—Dario Englot, M.D., Ph.D., has received a grant from the National Institutes of Health to support his research into better understanding brain connectivity disturbances in patients with focal epilepsy.
Protein ‘clumping’ linked to severe form of genetic epilepsy
Aug. 13, 2015—Researchers at Vanderbilt University for the first time have demonstrated in a mouse model that aggregation, the “clumping together” of abnormal proteins, can contribute to a severe form of genetic epilepsy.
Insights on lysosomal storage diseases
May. 14, 2015—A novel mechanism could point to new therapies for a group of inherited diseases that share pathological features.