Developmental Cell
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Microvilli in motion
Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border. Read MoreSep 19, 2019
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Building intestinal brush borders
Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease. Read MoreFeb 8, 2016
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Findings offer new insight on how cell division proteins work
A family of proteins with critical roles in cell division, synaptic transmission and cell migration don’t all function the way scientists thought they did, according to two new studies led by Vanderbilt researchers. Read MoreJan 28, 2016
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Microtubules act as cellular ‘rheostat’ to control insulin secretion
Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell. Read MoreDec 3, 2015
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VU study reveals factor’s new role in cell division, migration
Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery. Read MoreOct 30, 2014
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VU study points to central regulator of neuron development
Developmental biologist Chin Chiang, Ph.D., and his colleagues have discovered that Purkinje neurons in the cerebellum act as central regulators of neuronal development. Read MoreDec 12, 2013