Colleen Niswender
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Vanderbilt Kennedy Center announces 2025–26 Nicholas Hobbs Discovery Award recipients
The Vanderbilt Kennedy Center has announced its latest Nicholas Hobbs Discovery Awards, which recognize innovative research to improve the lives of people with intellectual and developmental disabilities. Colleen Niswender, Dr. Bill Nobis, Audrey Bowden and Laurie Cutting are the recipients for 2025–26, earning support for projects that address Rett syndrome, Dravet syndrome and other developmental epilepsies, and reading difficulties like dyslexia. Read MoreDec 4, 2025
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Warren Center for Neuroscience Drug Discovery researchers create new compound to potentially treat negative and positive symptoms of schizophrenia
Recent research from the Warren Center for Neuroscience Drug Discovery, published in the Journal of Medicinal Chemistry, resulted in the proposal of a novel target and mechanism for improving cognition—a negative symptom—while also treating positive symptoms of the disease. Read MoreFeb 13, 2025
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Warren Center for Neuroscience Drug Discovery researchers create new compound to potentially treat negative and positive symptoms of schizophrenia
We often think about diseases in terms of the symptoms they present. A cold might give you the sniffles or even GI distress, while malaria can give you fever, chills, or nausea... Read MoreJan 30, 2025
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Vanderbilt CTTC honors five pioneering faculty as newly inducted Master Innovators
The Center for Technology Transfer and Commercialization has honored five faculty members as 2024 Master Innovators for their groundbreaking research and transformative innovations. These pioneers, recognized for achievements spanning patents, startups and impactful technologies, exemplify Vanderbilt's dedication to translating academic excellence into societal advancements. Read MoreDec 5, 2024
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Potential schizophrenia treatment, discovered at Vanderbilt and being developed by Neumora Therapeutics, entering Phase 1 clinical trial
In just over two years, a Vanderbilt-Neumora collaboration has led to the Phase 1 clinical trial of a treatment for schizophrenia spectrum disorders, which affect 3.7 million adults in the United States. This is the third chemical compound discovered at the Warren Center for Neuroscience Drug Discovery to reach Phase 1 clinical trials. Read MoreDec 4, 2023
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Drug discovery efforts may lead to new Rett syndrome treatments
Vanderbilt University research-ers have relieved symptoms of Rett syndrome in a mouse model with a small molecule that works like the dimmer switch in an electrical circuit. Read MoreAug 24, 2017
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VUMC’s Rett Syndrome Clinic lands national recognition
Vanderbilt’s Rett Syndrome Clinic has been named a Rett Syndrome Clinical Research Center of Excellence by Rettsyndrome.org. Read MoreNov 17, 2016
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Study reveals possible ‘dimmer switch’ drug for Rett syndrome
Researchers at Vanderbilt University Medical Center have relieved symptoms in a mouse model of Rett syndrome with a drug-like compound that works like the dimmer switch in an electrical circuit. Read MoreMar 3, 2016
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Autism Speaks grant boosts Rett syndrome research
Colleen Niswender, Ph.D., research associate professor of Pharmacology, has received a three-year, $450,000 grant from the autism science and advocacy organization Autism Speaks to support studies investigating a possible new treatment for Rett syndrome. Read MoreJan 23, 2014
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Drug-like molecules aimed at improving treatment of Parkinson’s
Drug-like molecules described by Vanderbilt researchers could lead to Parkinson's treatments with fewer side effects. Read MoreSep 30, 2011
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New drug-like molecules could improve schizophrenia treatment
The discovery of new compounds that work in a fundamentally different way than those in existing schizophrenia medications may allow for more normal function of brain cells involved in schizophrenia. Read MoreSep 22, 2011
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Milestone in development of new treatment for ‘fragile X’
Researchers at Vanderbilt University Medical Center, in collaboration with Seaside Therapeutics in Cambridge, Mass., have achieved a milestone in the development of a potential new treatment for fragile X syndrome, the most common genetic cause of autism. Read MoreSep 15, 2011
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Neuroscience drug discovery center opens at Vanderbilt
Vanderbilt University Medical Center has established a new Center for Neuroscience Drug Discovery to accelerate research that may lead to new treatments for Parkinson's disease, schizophrenia and other disorders of the brain. Read MoreMar 11, 2011