Charles Hong
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Goal of new tissue-chip research is to assess efficacy of novel epilepsy drugs
An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an “organ-on-chip” model for two genetic forms of epilepsy. Read MoreSep 20, 2017
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NOTCH1 role in heart development
The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition. Read MoreJul 3, 2017
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Organ-on-a-chip mimics heart’s biomechanical properties
Scientists at Vanderbilt University have created a three-dimensional organ-on-a-chip that can mimic the heart’s amazing biomechanical properties in order to study cardiac disease, develop heart drugs. Read MoreFeb 22, 2017
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New method aids heart disease studies, drug discovery efforts
A team of Vanderbilt investigators developed a new method for rapidly generating heart muscle cells from stem cells. Read MoreJan 14, 2016
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New lead for ovarian cancer treatment
Combining inhibitors of the BMP signaling pathway with standard chemotherapy drugs may overcome drug resistance in ovarian cancer. Read MoreDec 10, 2015
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Collaboration seeks to develop new therapies for bone, other diseases
La Jolla Pharmaceutical Co. and Vanderbilt University have signed a research and license agreement covering Vanderbilt’s research program and intellectual property rights related to compounds that block bone morphogenetic protein (BMP) type-I receptors. The compounds have therapeutic potential in a broad range of diseases, including rare genetic disorders. Read MoreOct 1, 2015
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Delivering cells for heart repair
A polymer hydrogel material developed by Vanderbilt scientists improved the delivery of stem cells for heart repair. Read MoreJul 10, 2015
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Cancer signaling pathway blocker
Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer. Read MoreApr 3, 2015
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Growth factor blockade targets breast tumors
Inhibition of BMP growth factor signaling reduces breast tumor burden and metastasis. Read MoreAug 14, 2014
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Fishing for new anti-cancer drugs
Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug. Read MoreSep 18, 2013
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Vanderbilt’s Hong, Niswender elected to ASCI
Charles Hong, M.D., Ph.D., and Kevin Niswender, M.D., Ph.D., have been elected to membership in the American Society of Clinical Investigation (ASCI), one of the nation’s most respected medical honor societies. Read MoreApr 18, 2013
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Move out, cholesterol
Compounds developed at Vanderbilt could offer a whole new way to treat atherosclerosis. Read MoreDec 8, 2011