Brandt Eichman

Sonja Fulmer, a graduate of Chemical and Physical Biology Program who is now the deputy director of the FDA’s Digital Health Center of Excellence, sat down with us to discuss her experience studying basic science at Vanderbilt and how it played a role in her successful career. Read More

Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication is initiated in eukaryotes. Using Vanderbilt’s state-of-the-art instrumentation in the Center for Structural Biology’s Cryo-Electron Microscopy Facility, Eichman, Chazin and their colleagues provided detailed visualizations of a multi-functional protein in action, which sheds light on how DNA replication is initiated in humans. Read More

Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity. Read More

Vanderbilt researchers uncover the secret of the remarkable potency of the DNA toxin yatakemycin, which could someday be harnessed to fight cancer. Read More

Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair. Read More

Vanderbilt investigators have discovered details about the mechanism of an important DNA repair protein that maintains genome stability. Read More

A new class of DNA repair enzyme has been discovered which demonstrates that a much broader range of damage can be removed from the double helix in ways that biologists did not think were possible. Read More

Vanderbilt and Stanford investigators have discovered how a protein that's part of the DNA replication "machinery" helps cells tolerate DNA damage. Read More

Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer. Read More