Biovu
-
‘Bedside to Bench to Bedside: BioVU Resources in Discovery and Translational Research’ Jan. 26
The Vanderbilt Institute of Chemical Biology presents a BioVU panel discussion featuring Vanderbilt University Medical Center researchers Cheryl Gatto, Celeste Jones Paris, Robert Lavieri, Jillian Rhoads and Michael Orr. “Bedside to Bench to Bedside: BioVU Resources in Discovery and Translational Research” will be on Wednesday, Jan. 26, from 12:15 to 1:15 p.m. via Zoom. Read MoreJan 21, 2022
-
Gene discoveries give new hope to people who stutter
New research shows the potential to identify therapeutic directions that could improve outcomes for people who stutter. Read MoreDec 2, 2021
-
For more precise drug treatments, ‘squeeze’ the genome: study finds
Large-scale studies will be required to identify the complexity of genetic variations that affect how patients respond to a given drug and whether they will have side effects, according to researchers at Vanderbilt University Medical Center. Read MoreJul 22, 2021
-
Probing statin-associated diseases with genetics
Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases. Read MoreJul 12, 2021
-
Study finds genetic risk factors for severe COVID-19 illness
A massive worldwide collaboration including researchers from Vanderbilt University Medical Center (VUMC) has identified several genetic factors associated with SARS-CoV-2 infection and severe COVID-19 illness. Read MoreJul 8, 2021
-
Genetics of hydrocephalus
Fluid build-up in the brain — hydrocephalus — increases pressure and risk for brain damage; Vanderbilt researchers have now identified genes and signaling pathways associated with the condition. Read MoreJul 8, 2021
-
Gene variant linked to unnecessary bone marrow biopsies in African Americans
A gene variant that lowers white blood cell levels and is common in individuals with African ancestry contributes to unnecessary bone marrow biopsies, according to a study published June 28 in JAMA Internal Medicine. The findings, led by investigators at VUMC, are an example of how using genetic data could reduce a health disparity. Read MoreJun 28, 2021
-
Codeine metabolizer status in clinical practice
Vanderbilt researchers have developed a response score using genetic and clinical information to aid prescribing of the widely used pain medication codeine. Read MoreApr 5, 2021
-
New tool to probe genetic mechanisms of disease
Vanderbilt Genetics Institute investigators have added a new method to the computational genetics toolbox. Their approach, described in the journal Nature Genetics, integrates vast genomics datasets to predict gene expression and facilitate discovery of genetic mechanisms underlying human diseases. Read MoreOct 22, 2020
-
Genes spell penicillin allergy risk
Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction. Read MoreOct 1, 2020
-
EHRs, biobanks and Mendelian diseases
Electronic health records and biobanks can be effectively combined to detect and study Mendelian diseases such as cystic fibrosis. Read MoreApr 30, 2020
-
Vanderbilt-led team discovers new genetic disease and defines underlying mechanism
An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms. Read MoreJan 13, 2020
-
Getting the goods on obesity
Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit. Read MoreNov 19, 2019
-
VUMC drug repurposing initiative gaining momentum
Drug repurposing involves establishing an additional approved indication for a drug already at market. Read MoreApr 19, 2018
-
Nashville Biosciences created to leverage wealth of data
Officials with Vanderbilt University Medical Center announced the creation of a wholly owned subsidiary, Nashville Biosciences, to harness the power of its extensive genomic and bioinformatics resources to advance drug and diagnostics discovery and development. Read MoreApr 5, 2018
-
Grant bolsters study of potential new therapy for C. diff infection
According to the Centers for Disease Control and Prevention, in 2011 in the United States there were almost half a million Clostridium difficile infections, and one in 11 patients 65 or older with a healthcare-associated C. diff infection died within 30 days of diagnosis. Read MoreMar 22, 2018
-
Study spots undiagnosed genetic diseases in EHR
Patients diagnosed with heart failure, stroke, infertility and kidney failure could actually be suffering from rare and undiagnosed genetic diseases. Read MoreMar 15, 2018
-
Cannabis compound reduces seizures
Cannabidiol (CBD) oils reduced seizures in patients with difficult-to-treat epilepsy, Vanderbilt investigators have found. Read MoreFeb 26, 2018
-
BioVU focus of Research Enterprise Forum Jan. 31
The School of Medicine will host a Research Enterprise Forum from 3 to 4 p.m. Wednesday, Jan. 31. Read MoreJan 10, 2018
-
BioVU MEGA Project fall update is Dec. 5
The BioVU MEGA Project fall 2017 update is scheduled for 4 p.m. Tuesday, Dec. 5, in Light Hall, Room 208. Read MoreNov 29, 2017