Biovu
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Gene discoveries give new hope to people who stutter
New research shows the potential to identify therapeutic directions that could improve outcomes for people who stutter. Read MoreDec 2, 2021
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For more precise drug treatments, ‘squeeze’ the genome: study finds
Large-scale studies will be required to identify the complexity of genetic variations that affect how patients respond to a given drug and whether they will have side effects, according to researchers at Vanderbilt University Medical Center. Read MoreJul 22, 2021
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Probing statin-associated diseases with genetics
Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases. Read MoreJul 12, 2021
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Study finds genetic risk factors for severe COVID-19 illness
A massive worldwide collaboration including researchers from Vanderbilt University Medical Center (VUMC) has identified several genetic factors associated with SARS-CoV-2 infection and severe COVID-19 illness. Read MoreJul 8, 2021
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Genetics of hydrocephalus
Fluid build-up in the brain — hydrocephalus — increases pressure and risk for brain damage; Vanderbilt researchers have now identified genes and signaling pathways associated with the condition. Read MoreJul 8, 2021
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Codeine metabolizer status in clinical practice
Vanderbilt researchers have developed a response score using genetic and clinical information to aid prescribing of the widely used pain medication codeine. Read MoreApr 5, 2021
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New tool to probe genetic mechanisms of disease
Vanderbilt Genetics Institute investigators have added a new method to the computational genetics toolbox. Their approach, described in the journal Nature Genetics, integrates vast genomics datasets to predict gene expression and facilitate discovery of genetic mechanisms underlying human diseases. Read MoreOct 22, 2020
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Genes spell penicillin allergy risk
Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction. Read MoreOct 1, 2020
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EHRs, biobanks and Mendelian diseases
Electronic health records and biobanks can be effectively combined to detect and study Mendelian diseases such as cystic fibrosis. Read MoreApr 30, 2020
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Vanderbilt-led team discovers new genetic disease and defines underlying mechanism
An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms. Read MoreJan 13, 2020
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Getting the goods on obesity
Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit. Read MoreNov 19, 2019
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VUMC drug repurposing initiative gaining momentum
Drug repurposing involves establishing an additional approved indication for a drug already at market. Read MoreApr 19, 2018
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Nashville Biosciences created to leverage wealth of data
Officials with Vanderbilt University Medical Center announced the creation of a wholly owned subsidiary, Nashville Biosciences, to harness the power of its extensive genomic and bioinformatics resources to advance drug and diagnostics discovery and development. Read MoreApr 5, 2018
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Grant bolsters study of potential new therapy for C. diff infection
According to the Centers for Disease Control and Prevention, in 2011 in the United States there were almost half a million Clostridium difficile infections, and one in 11 patients 65 or older with a healthcare-associated C. diff infection died within 30 days of diagnosis. Read MoreMar 22, 2018
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Study spots undiagnosed genetic diseases in EHR
Patients diagnosed with heart failure, stroke, infertility and kidney failure could actually be suffering from rare and undiagnosed genetic diseases. Read MoreMar 15, 2018
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Cannabis compound reduces seizures
Cannabidiol (CBD) oils reduced seizures in patients with difficult-to-treat epilepsy, Vanderbilt investigators have found. Read MoreFeb 26, 2018
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BioVU anniversary
Last week the BioVU Operations Oversight Board celebrated the 10-year anniversary of the launching of BioVU, Vanderbilt University Medical Center’s massive biobank. Read MoreFeb 23, 2017
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Rheumatoid subtypes explored by PheWAS
A computer-based method pioneered at Vanderbilt is being used to compare subtypes of rheumatoid arthritis. Read MoreOct 7, 2016
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VUMC chosen for leadership role in NIH Precision Medicine Initiative Cohort Program
Vanderbilt University Medical Center (VUMC) has been chosen by the National Institutes of Health (NIH) to be the Data and Research Support Center for the Precision Medicine Initiative Cohort Program, a landmark study of genetic, environmental and lifestyle factors affecting the health of a million or more people, federal officials have announced. Read MoreJul 7, 2016
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VUMC and Celgene Corporation enter into research agreement to accelerate development of next-generation therapeutics
Vanderbilt University Medical Center has entered into a strategic research agreement with Celgene Corporation, a biopharmaceutical company based in Summit, New Jersey. Read MoreApr 4, 2016