Atherosclerosis

Vanderbilt research found that sleep irregularity — chronically disrupted sleep and highly variable sleep durations night after night — may increase the risk for atherosclerosis. Read More

A new model suggests that a protein involved in the generation of high-density lipoprotein (HDL) works differently than previously thought. Read More

Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins. Read More

Researchers at Vanderbilt University Medical Center have identified potential new targets for the prevention of atherosclerosis through the enhancement of autophagy, a natural process for recycling damaged cellular material. Read More

A small-molecule “scavenger” that reduces inflammation and formation of atherosclerotic plaque in blood vessels in mice potentially could lead to a new approach for treating atherosclerosis in humans, according to researchers at Vanderbilt University Medical Center. Read More

Consumption of soy foods may shape the microbiome and protect against hypertension only in individuals with soy-responsive microbiota, Vanderbilt researchers have discovered. Read More

Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis. Read More

A new imaging method makes it possible to directly measure cell division and changes in metabolism in atherosclerotic plaques. Read More

Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease. Read More

When atherosclerosis develops in the coronary arteries over a period of time, complete blockage of that artery can result in chest pain, shortness of breath and decreased quality of life. Read More

A newly identified “atheroprotective” gene is a tool for exploring plaque pathophysiology and may be a good target for therapies to slow atherosclerosis progression. Read More

Vanderbilt researchers have discovered a new target for the prevention of atherosclerotic plaque development and cardiovascular disease. Read More

In some cases, HDL, the "good cholesterol," may not function properly and may actually accelerate atherosclerosis. Read More

Vanderbilt University scientists have discovered a potential new strategy for lowering cholesterol and triglyceride levels and stopping atherosclerosis and fatty liver disease. Read More

Compounds developed at Vanderbilt could offer a whole new way to treat atherosclerosis. Read More

A discovery about the causes of atherosclerosis, a cause of heart attacks and strokes, may lead to new treatments. Read More