Arts And Science Research

This past academic year, seven graduate students and one undergraduate student participated in the 2025 Merck Compound Challenge. Created in 2018, the competition gives teams from around the world 48 hours to create a proposed route of chemical steps from a commercial chemical they believe will make the final compound. Read More

Pet parrots often outlive their owners, and Vanderbilt researchers want to know why—because uncovering the biological mechanisms behind exceptional longevity could one day help safely extend the lives of humans. With the support of a new $1.3 million grant from the W.M. Keck Foundation, Vanderbilt biologist Gianni Castiglione is taking a bold approach to aging research: reverse-engineering how birds live three to four times longer than similarly sized mammals to identify safe, effective genetic targets for human aging therapies. Read More

A collaboration among VUMC, the College of Arts and Science, the School of Medicine and the School of Engineering has led to some higher-order “hitchhikers” that can make immunotherapy cancer treatments more effective. Associate Professor John Wilson’s lab devised a way to piggyback cancer-fighting nanobodies onto molecules that naturally accumulate around tumors—getting the treatment where it needs to go. Read More

In this episode of Quantum Potential, Amanda Little, writer-in-residence at Vanderbilt’s College of Arts and Science, joins Provost C. Cybele Raver to discuss how journalism can highlight the tipping points humanity faces and how people-first storytelling can move us from observation to action. Read More

The Office of Postdoctoral Affairs, in partnership with the Vanderbilt Postdoctoral Association, announced the 2025 award winners at the Spring Postdoc Awards Ceremony on May 21. The event highlighted the vital contributions that postdocs make across various disciplines at the university.   Read More

A recent study from the labs of Lars Plate and Jens Meiler, published in the Proceedings of the National Academy of Sciences of the United States of America, analyzed both selectively responsive and poorly responsive variants of cystic fibrosis and revealed the molecular determinants of drug response. Read More

Danial Asgari, a postdoctoral researcher in the Tate Lab, and Ann Tate, associate professor of Biological Sciences, recently published a study in Molecular Biology and Evolution titled “How the Structure of Signaling Regulation Evolves: Insights from an Evolutionary Model.” Their findings show that negative feedback loops (or NFLs) acting closer to a cell’s final decisions, such as turning genes on or off, are especially resistant to evolutionary change. Read More

While we know that intermediate-mass black holes should exist, little is known about their origins or characteristics—they are considered the rare “missing links” in black hole evolution. However, four new studies have shed new light on the mystery. The research was led by a team in the lab of Assistant Professor of Physics and Astronomy Karan Jani, who also serves as the founding director of the Vanderbilt Lunar Labs Initiative. Read More

The National Center for Science Education has named Vanderbilt University’s Evolutionary Studies Initiative as one of its 2025 recipients of the prestigious Friend of Darwin award. This national honor recognizes ESI’s outstanding contributions to advancing public understanding of evolution through interdisciplinary research, education and outreach. Read More

Vanderbilt has announced eleven awardees in the latest round of its Innovation Catalyst Fund, an initiative that supports translational research that has promising commercial potential. Read More

Our past has something to say. 2025 Guggenheim Fellow Larisa DeSantis is ready to translate. Read More

Gertrude Conaway Vanderbilt Professor of English Major Jackson sees poetry as an art best appreciated in communion with others and approached through the senses as much as the intellect. He believes deeply in the power of poetry to break down barriers and foster understanding. Read More

Josh Clinton, Abby and Jon Winkelried Chair and professor of political science, and co-director of the Vanderbilt Center for the Study of Democratic Institutions, joins Provost C. Cybele Raver to discuss how transparency and increasing public literacy about statistics—including an awareness of limitations—can disrupt Americans’ mounting distrust in polling data. Read More

Vanderbilt University has joined the Urban Humanities Network (UHN) as a consortium campus, solidifying the university’s place among leading institutions at the forefront of urban humanities scholarship. Established in 2022, UHN unites universities, organizations, and researchers dedicated to interdisciplinary study within the urban humanities, which operates at the nexus of humanities, urbanism, and design. Read More

Since its inception in 1999, the VBI has spearheaded interdisciplinary neuroscience research and education. Over the years, the VBI has grown into a vibrant, trans-institutional hub that spans the School of Medicine Basic Sciences, the College of Arts and Science, the School of Engineering, the Peabody College of education and human development, and other schools and departments throughout Vanderbilt and Vanderbilt University Medical Center. Read More

See how historian Jane Landers and her team are rescuing enslaved Africans’ stories from oblivion and honoring thousands of lives. Read More

New work from the Castiglione lab and that of collaborator, Elia Duh (Johns Hopkins), is shaping the way is shaping the way we understand the evolutionary limits of energy production. He discovered that the horse, an oft-studied, physiological powerhouse, evolved an enigmatic and ancient mutation that enables horses and their relatives to produce extreme amounts of energy while avoiding deleterious side effects. Read More

As Cornelius Vanderbilt Professor of Physics and chair of the Department of Physics and Astronomy, Julia Velkovska studies the tiny particles that form our universe. She focuses on how nuclear matter behaves when confronted with extreme density and temperatures (think trillions of degrees)—similar to the conditions existing microseconds after the big bang, right as the universe was starting to take shape. Just this year, Velkovska and her team of physicists were awarded the 2025 Breakthrough Prize in Fundamental Physics, along with 13,508 colleagues across four landmark CERN experiments. The prize honors decades of work expanding our understanding of the physical universe. Read More

Learn about the women who inspire Steven Townsend in his breakthrough research that puts a spotlight on women, their health and discoveries around the healing powers of breast milk. Read More

Fat and protein molecules are essential to human brain health, and there are microscopic transport hubs that make sure the right molecules get to the right cells. If the proteins aren’t interacting properly, they can wind up in the wrong places—a problem that’s been linked to diseases like Alzheimer’s, Parkinson’s and ALS. Research in Associate Professor Lauren Jackson’s lab has uncovered how those proteins interact. Read More